135 citations
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December 2006 in “PLoS Medicine” Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
79 citations
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August 1998 in “The Journal of Cell Biology” Keratin 16 delays skin maturation and affects skin and hair development in mice.
74 citations
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November 2000 in “Archives of Dermatology” Salicylic acid can safely exfoliate and regenerate skin without causing inflammation.
34 citations
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June 2005 in “Developmental dynamics” Runx3 helps determine hair shape.
32 citations
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August 2024 in “Journal of Investigative Dermatology” In vitro skin models are improving but still need more innovation to fully replicate human skin.
25 citations
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February 2021 in “Diabetes” Dock5 is important for skin healing and could help treat diabetic wounds.
24 citations
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January 2023 in “Frontiers in Medicine” Moist Exposed Burn Ointment speeds up healing of diabetic wounds.
23 citations
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May 2023 in “Cell Proliferation” TGF-β and FGF pathways are crucial for skin development and regeneration.
23 citations
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March 2023 in “eLife” Stem cell differentiation involves gradual chromatin changes and dynamic gene activity.
22 citations
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May 2011 in “Molecular Biology of the Cell” Integrin-linked kinase is crucial for normal skin healing.
16 citations
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July 2008 in “BMC Genomics” Alpha 6 + /MHCI - cells have stem cell traits and are similar to mouse hair follicle stem cells.
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May 2014 in “Journal of Biological Chemistry” A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.
13 citations
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April 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
12 citations
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September 2024 in “JID Innovations” Skin-on-a-chip devices better mimic human skin for research.
12 citations
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June 2021 in “Stem Cell Investigation” Aloe vera heals deep second-degree burns faster and better than mesenchymal stem cells.
12 citations
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October 2014 in “Journal of Applied Animal Research” Bakerwali goat skin thickens with age, especially on the neck, and shows strong lipid reactions in the keratin layer.
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August 2007 in “Human Molecular Genetics” Lymphotoxin-β is crucial for proper skin development in embryos.
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January 2021 in “Acta Cirúrgica Brasileira” Dipotassium glycyrrhizinate helps wounds heal faster, especially in the early stages.
8 citations
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January 2023 in “International journal of molecular sciences” Transglutaminase activity is important for skin and is found in both mammals and birds.
8 citations
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June 2022 in “Scientific Reports” LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
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November 2019 in “Tissue Engineering Part A” Functionalized collagen scaffolds applied prenatally greatly improve skin regeneration.
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January 2017 in “Journal of Oral and Maxillofacial Pathology” Keratoacanthomas on lips may originate differently than those on skin.
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January 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” NIPP1 is important for healthy skin and could help treat skin inflammation.
5 citations
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January 2021 in “Frontiers in cell and developmental biology” Skin cysts might help advance stem cell treatments to repair skin.
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April 2024 in “The Journal of Cell Biology” Caspase-1 helps hair stem cells move to heal wounded or inflamed skin.
2 citations
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March 2014 in “The Egyptian Journal of Histology” Bone marrow-derived stem cells greatly improve skin wound healing in rats.
1 citations
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January 2024 in “Microorganisms” Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.
1 citations
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January 2021 in “Brazilian Journal of Medical and Biological Research” Constant light exposure during pregnancy changes newborn rabbits' skin, affecting hair follicles, skin thickness, and pigment cells.
March 2025 in “Nature Communications” NSC167409 can effectively inhibit the virus causing hand, foot, and mouth disease.
November 2023 in “Frontiers in Medicine” The method effectively mimics shaving damage on skin for testing skincare products.