61 citations
,
November 2004 in “Annals of the Academy of Medicine Singapore” Hair follicle stem cells are mainly in the bulge region and can help repair skin and form hair and glands, but more research is needed to fully understand them.
58 citations
,
June 1987 in “Archives of Dermatological Research” EGF and FGF boost hair cell growth, hydrocortisone slows it, and minoxidil doesn't affect it.
57 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
46 citations
,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
39 citations
,
January 2015 in “International journal for parasitology/International Journal for Parasitology” Epidermal keratinocytes start wound healing and inflammation after schistosome infection.
22 citations
,
February 2013 in “Wound Repair and Regeneration” Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.
20 citations
,
July 2013 in “PLoS ONE” Targeting EGFR may help reduce hair loss from chemotherapy.
19 citations
,
September 2019 in “PLOS genetics” Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
19 citations
,
March 2018 in “Journal of Investigative Dermatology” The gene Msx2 is crucial for hair follicle regeneration during wound healing.
15 citations
,
August 2013 in “Stem Cells and Development” The method increases stem-like cells for better skin regeneration.
12 citations
,
February 1997 in “British Journal of Dermatology” The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.
11 citations
,
March 2013 in “Gene” A certain genetic variation in the IL1A gene may lower the risk of a hair loss condition in Chinese people.
10 citations
,
January 2018 in “Organogenesis” Porcine acellular dermal matrix treatment helps wounds heal faster and reduces scarring by affecting Jag1 in skin stem cells.
10 citations
,
September 1997 in “Molecular carcinogenesis” Mirex seems to promote a unique group of skin cells different from those affected by another tumor promoter, TPA.
10 citations
,
February 2020 in “Endocrine” Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.
8 citations
,
January 2019 in “Experimental Dermatology” The 3D skin model is better for hair growth research and testing treatments.
7 citations
,
October 2013 in “Methods in molecular biology” These methods help understand DNA changes in mouse skin.
6 citations
,
June 2021 in “Developmental biology” Dermal EZH2 controls skin cell development and hair growth in mice.
5 citations
,
January 2016 in “Stem Cells International” Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.
2 citations
,
July 2020 in “Electromagnetic Biology and Medicine” Low-frequency electromagnetic fields help regenerate hair follicles using a mix of skin cells.
2 citations
,
December 2018 Alopecia frontal fibrosante affects facial vellus hair and can be diagnosed with dermatoscopy.
2 citations
,
November 2015 in “Actas Dermo-Sifiliográficas” Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.
1 citations
,
August 2024 in “Transgenic Research” Activated β-catenin affects hair growth and skin thickness, and changes are reversible.
1 citations
,
November 2020 in “Biochemical Society transactions” Different types of skin stem cells can change and adapt, which is important for developing new treatments.
1 citations
,
February 2021 in “Scholars international journal of anatomy and physiology” Different forms of FGF5 either promote or inhibit hair growth.
May 2026 in “Journal of Health and Allied Sciences NU” Optimized culture conditions improve human epidermal stem cell growth for skin regeneration.
April 2024 in “Journal of pharmacy & pharmacognosy research” A compound from Calophyllum inophyllum L. leaf may help treat non-small cell lung cancer.
January 2021 in “Acta Scientiae Veterinariae” Levothyroxine effectively treated a dog's skin and hair problems caused by hypothyroidism.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Dermal EZH2 controls skin cell growth and differentiation in mice.
April 2017 in “Journal of Investigative Dermatology” The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.