June 2006 in “Experimental dermatology” Hair follicle bulge cells are important for hair survival and help heal the skin after injury, which might be relevant for understanding hidradenitis suppurativa.
15 citations
,
February 2021 in “Cells” Transfected cells with VEGF and FGF2 genes improve skin wound healing by enhancing blood flow and regeneration.
92 citations
,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
8 citations
,
November 2024 in “EMBO Molecular Medicine” Targeting JAK-STAT1 can reduce inflammation and promote hair growth in conditions linked to EGFR deficiency.
7 citations
,
January 2022 in “Biomedicines” Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.
6 citations
,
December 2023 in “Journal of Clinical Medicine” Abnormal growth factor metabolism may link psoriasis and metabolic syndrome, and obesity can affect psoriasis treatment effectiveness.
August 2016 in “Journal of Investigative Dermatology” EZH2 is essential for hair growth and skin cell development.
1 citations
,
March 2023 in “International Journal of Trichology” Platelet-rich plasma didn't increase hair length but may help keep hair follicles alive.
January 2006 in “Durham e-Theses (Durham University)” Id proteins, especially Id2 and Id3, are crucial for hair follicle development and stem cell regulation.
4 citations
,
May 2021 in “The American Journal of Surgical Pathology” Cutaneous Lymphadenoma is a unique skin tumor with specific protein markers and common gene mutations that may cause continuous cell growth.
March 2025 in “Nature Communications” NSC167409 can effectively inhibit the virus causing hand, foot, and mouth disease.
44 citations
,
September 2016 in “American Journal Of Pathology” Neural crest-derived progenitor cells in the cornea could help treat corneal issues without transplants.
31 citations
,
April 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.
8 citations
,
July 2015 in “European journal of histochemistry” Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.
212 citations
,
August 2004 in “Proceedings of the National Academy of Sciences” Hair follicle cells can create new blood vessels in the skin.
854 citations
,
February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
September 2017 in “Journal of Investigative Dermatology” Ovol2 is essential for normal skin and hair regeneration.
1 citations
,
January 2011 in “International Journal of Trichology” Hair follicle stem cells have significant potential for treating various disorders.
21 citations
,
January 2023 in “International Journal of Molecular Sciences” S100A6 protein is linked to disease progression, especially in cancers.
78 citations
,
October 2007 in “Journal of Investigative Dermatology” Delta1 is crucial for controlling skin cell growth and preventing tumors in mice.
23 citations
,
March 2023 in “eLife” Stem cell differentiation involves gradual chromatin changes and dynamic gene activity.
25 citations
,
January 2015 in “World journal of stem cells” Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.
73 citations
,
January 2002 in “Journal of Investigative Dermatology” Epidermal stem cells don't use gap junctions to communicate.
1 citations
,
February 2002 in “The Lancet” Keratinocytes might turn into stem cells, but more research is needed to confirm this.
21 citations
,
October 2013 in “Molecular Biology of the Cell” The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
7 citations
,
February 2023 in “Inflammation and Regeneration” The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.
3 citations
,
May 2013 in “International journal of molecular sciences” Epidermal stem cells show promise for treating orthopedic injuries and diseases.
February 2011 in “Journal of Investigative Dermatology” New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.
3 citations
,
December 2024 in “Journal of Animal Physiology and Animal Nutrition” FGF20 is essential for hair follicle stem cell growth and development in fine-wool sheep.
Quercetin can boost hair follicle stem cell growth in cashmere goats, potentially improving cashmere quality.