research Notch1 Signaling Regulates Wound Healing via Changing the Characteristics of Epidermal Stem Cells
Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.
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780-810 / 1000+ results research Successful treatment of epidermal growth factor receptor inhibitor–induced alopecia with doxycycline
Doxycycline can effectively treat hair loss caused by EGFR inhibitors.
research The lipide composition of epidermis and dermis of mice undergoing carcinogenesis by methylcholanthrene.
Cholesterol and phospholipids increase in mouse skin during cancer development, with differences between male and female skin.
research Tenascin-C expressing touch dome keratinocytes exhibit characteristics of all epidermal lineages
Touch dome keratinocytes in adult skin have traits of different skin cell types.
research Preliminary studies of hair follicle regeneration by injections of epidermal stem cells and dermal papilla cells into nude mice
Injected cells show potential for hair growth.
research Single cell transcriptomics of human epidermis reveals basal stem cell transition states
Basal stem cells in the skin have distinct types that are crucial for skin structure and health.
research Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle
Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.
research SPRY1 Deficiency in Keratinocytes Induces Follicular Melanocyte Stem Cell Migration to the Epidermis through p53/Stem Cell Factor/C-KIT Signaling
SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
research ELL Facilitates RNA Polymerase II–Mediated Transcription of Human Epidermal Proliferation Genes
ELL is crucial for gene transcription related to skin cell growth.
research Induction of ornithine decarboxylase activity in hairless rat epidermis as a pharmacological model: validation of the animal model
Female rats aged 8 weeks are best for this model.
research Self-assembled complete hair follicle organoids by coculture of neonatal mouse epidermal cells and dermal cells in Matrigel
Scientists created complete hair-like structures by growing mouse skin cells together in a special gel.
research Estrogen modulates mesenchymal-epidermal interactions in the adult nipple
Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
research Epidermal growth factor promotes mesenchymal stem cell-mediated wound healing and hair follicle regeneration.
Epidermal growth factor helps stem cells heal wounds and regenerate hair follicles faster.
research Transcriptional Control of Epidermal Stem Cells
Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
research A novel approach to manage skin toxicity caused by therapeutic agents targeting epidermal growth factor receptor
New treatment with green tea polyphenols and nicotinamide improves skin problems from cancer therapy.
research Human papillomavirus 60-positive epidermal cyst and wart at a nonpalmoplantar location
HPV 60 may cause cysts and warts on the face, not just hands and feet.
research A Sensitive Assay for the Enzyme Activity in Hair Follicles and Epidermis that Catalyses the Peptidyl-Arginine-Citrulline Post-translational Modification
A more sensitive assay was developed to detect enzyme activity converting arginine to citrulline in hair follicles.
research Keratin metabolism in the epidermis and hair of mice with experimental diabetes
Diabetes changes keratin in skin and hair, affecting their health.
research Epidermal-Derived Hedgehog Signaling Drives Mesenchymal Proliferation during Digit Tip Regeneration
Epidermal signaling helps regenerate fingertip tissue.
research Autologous smashed follicular dermal graft with epidermal cell suspension in chronic nonhealing leg ulcers
A new treatment using skin and hair cells may help heal stubborn leg ulcers effectively and safely.
research Author response: NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures
NuMA-microtubule interactions are crucial for proper skin structure and hair growth.
research Epidermal Stem Cells in Orthopaedic Regenerative Medicine
Epidermal stem cells show promise for treating orthopedic injuries and diseases.
research Expression of type 1 5α-reductase and metabolism of testosterone in reconstructed human epidermis (SkinEthic®): a new model for screening skin-targeted androgen modulators
The study created a new method to test drugs that affect hormone processing in skin.
research Expression of retinoic acid receptors and dermal-epidermal interactions during mouse skin morphogenesis
Retinoic acid can change skin development, like turning scales into feathers or forming glands.
research A human serum‐enriched medium formulation supports high viability and marker expression in primary melanocyte cultures from the outer root sheath and epidermis
A human serum-enriched medium effectively supports melanocyte growth and activity without using animal-derived supplements.
research A new in vitro culture system to produce a fully differentiated epidermis from human hair follicle outer root sheath cells
Researchers developed a method to grow skin-like tissue from hair cells.
research Fluid Loss Through Epidermis of the Rat and Factors Affecting It.
Fluid loss through rat skin is minimal when inactive but increases with skin activity and hair growth.
research 1α,25-Dihydroxyvitamin D3 accelerates skin wound re-epithelialization by promoting epidermal stem cell proliferation and differentiation through PI3K activation: an in vitro and in vivo study
Vitamin D3 speeds up skin healing by helping skin stem cells grow and develop.
research Deimination in epidermal barrier and hair formation
Enzymes that change arginine to citrulline are important for skin barrier and hair formation, and their malfunction can lead to skin conditions and hair disorders.
research Region-specific reversal of epidermal planar polarity in the rosette fancy mouse
Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.