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Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.

Mutations in the p63 gene affect skin adhesion, barrier integrity, and hair growth.

New treatments may restore cancer-blocking proteins, slow prostate cancer, identify drug targets, and potentially regrow hair.

CEP135 may predict cancer outcomes, and targeting PLK1 could help treat certain sarcomas.

PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.

The oncoprotein causes abnormal hair growth without increasing skin cancer risk.

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

Glycerol may improve wound healing and prevent keloids, a device can measure itch intensity, male pattern baldness is highly heritable, and fumaric acid esters may work for psoriasis by causing cell death in T cells.

Advances in RNA research and skin models offer hope for better skin healing without scarring.

ETS2 is crucial in squamous cell carcinoma development and could be a therapeutic target.

Merkel cells stabilize nerve endings in the skin, and they change independently of each other.

Reduced PER3 gene activity in hair follicles is linked to irregular sleep in schizophrenia.

EGFR helps control how hair grows and forms without needing p53 protein.

The study created a mouse model to mimic degenerative diseases for testing tissue repair and new therapies.

Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.

Humans have ancient DNA from Neanderthals and other lineages in their chromosomes, affecting traits and evolution.

Ingenol mebutate gel changes gene expression related to skin development and immune response in actinic keratosis.

Removing the VDR gene in skin cells reduces their growth and affects hair-related genes.

Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Impaired LEF1 activation speeds up skin cell development in Hutchinson-Gilford Progeria Syndrome.

Pyrene excimer nucleic acid probes are promising for detecting biomolecules accurately with potential for biological research and drug screening.

A new genetic mutation causing Xeroderma Pigmentosum was found in an 8-year-old girl, affecting her DNA repair.

Estrogen receptors affect hair growth, with ER beta slowing down the hair cycle changes caused by ER alpha.

A new method using gold nanoshells and infrared light effectively delivers siRNA to cancer and stem cells with precision and minimal damage.

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

ETS2 drives cancer progression in squamous cell carcinoma and is linked to poor patient outcomes.

Different Hairless isoforms affect Vitamin D receptor activity in hair regulation, with one repressing and the other stimulating it.

Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.