research 17β-Estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-α pathway
Estradiol stops hair growth in mice, but an antagonist can reverse this effect.
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research GLI2-specific Transcriptional Activation of the Bone Morphogenetic Protein/Activin Antagonist Follistatin in Human Epidermal Cells
GLI2 increases follistatin production in human skin cells.
research Essential Role of Polarity Protein Par3 for Epidermal Homeostasis through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance
The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
research Col4a2-eGFPmouse model reveals the molecular and functional dynamics of basement membrane remodelling in hair follicle morphogenesis
Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.
research 1365 Elf5, a novel regulator of skin stem/progenitor cells fate during skin development?
Elf5 is important for skin stem cell growth and could help treat skin and hair problems.
research Epidermal growth factor receptor inhibitors and hair
research Erythropoietin induces insulin-like growth factor-1 from three-dimensional culture of human dermal papilla cells
Erythropoietin can promote hair growth by increasing IGF-1 in hair cells.
research Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis
ABCG2 protein marks stem-like skin cells in human epidermis.
research Reconstructed Tissue-engineered Skin with ES Cell-derived Epidermal Stem Cells and Collagen Sponge
Engineered skin using stem cells and collagen sponge effectively healed and regenerated complex skin features in mice.
research Abstract 12: LGR6+ Epithelial Stem Cell Augmentation of Fracture Healing
LGR6+ stem cells may improve bone healing.
research A 5'-upstream region of a bovine keratin 6 gene confers tissue-specific expression and hyperproliferation-related induction in transgenic mice.
A specific gene region can control targeted and responsive gene expression in mice, useful for skin disorder treatments.
research Commensal microbe regulation of skin cells in disease
research LB1256 TRIV-509, a dual inhibitor of KLK5 and KLK7, rapidly improves barrier integrity and markers of epidermal differentiation in atopic dermatitis skin explants
TRIV-509 quickly improves skin barrier and cell health in atopic dermatitis.
research The incidence and management of cutaneous adverse events of the epidermal growth factor receptor inhibitors
EGFR inhibitors can cause various skin issues during cancer treatment, and managing these is important for patient care.
research Edar Signaling in the Control of Hair Follicle Development
Edar signaling is crucial for proper hair follicle development and function.
research Expression and distribution of EPHA4 and Ephrin A3 in Aohan fine-wool sheep skin
EPHA4 and Ephrin A3 are found in the skin of Aohan fine-wool sheep.
research Intercellular junctions in normal epidermis
Desmosomal adhesion is essential for healthy skin structure and function.
research The functions of ocu-miR-205 in regulating hair follicle development in Rex rabbits
ocu-miR-205 affects hair density in Rex rabbits by promoting cell changes that lead to more hair follicles entering resting phases.
research Unwanted hair growth induced by topical epidermal growth factor during wound healing: true or myth?
Topical EGF may cause unexpected hair growth during wound healing.
research An eGFP-Col4a2 mouse model reveals basement membrane dynamics underlying hair follicle morphogenesis
Basement membrane changes are crucial for hair follicle development.
research 312 CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells
The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.
research 707 Guiding skin organoid generation via extracellular matrix cues and spatially controlled morphogen gradients
Scientists improved how to make skin-like structures from stem cells using special gels and a device that controls growth signals, leading to better hair and skin features.
research Ephrin-A3 not only increases the density of hair follicles but also accelerates anagen development in neonatal mice
Ephrin-A3 helps increase and speed up hair growth in baby mice.
research 459 Estetrol prevents catagen progression in healthy and female pattern hair loss hair follicles ex vivo
Estetrol may help prevent hair loss and support hair growth in women.
research Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken
Gene regulation evolved differently in mouse and chicken skin, but remained stable in their trunks.
research Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle
Sgk3 is essential for normal hair follicle growth and maintenance.
research Regulatory role of LEF-1 in the proliferation of Arbas White Cashmere goat dermal papilla cells
LEF-1 boosts cell growth in goat hair follicles, aiding cashmere production.
research Regulation of Hair Follicle Development: An In Vitro Model for Hair Follicle Invasion of Dermis and Associated Connective Tissue Remodeling.
research Expression Level of Prostaglandin D2 Receptor 2 Regulates Hair Regression
Higher levels of the DP2 receptor may lead to hair loss.
research Lineage potential, plasticity and environmental reprogramming of epithelial stem/progenitor cells
Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.