51 citations
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August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
51 citations
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September 2000 in “Acta dermato-venereologica” PPAR alpha may help in hair growth and could be a target for treatment.
51 citations
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November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Beard cells, unlike scalp cells, produce growth factors in response to testosterone, which may explain differences in hair growth.
50 citations
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May 2021 in “Frontiers in immunology” Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.
48 citations
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April 2019 in “PloS one” Alopecia areata patients have more Propionibacterium acnes and less Staphylococcus epidermidis on their scalps.
45 citations
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May 2024 in “International Journal of Molecular Sciences” Alopecia areata is caused by immune attacks on hair follicles, affecting hair growth and quality of life.
42 citations
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July 2021 in “Frontiers in Cell and Developmental Biology” Oral mucosa heals with minimal scarring, offering insights for scarless wound healing.
41 citations
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July 2019 in “Clinical Cosmetic and Investigational Dermatology” The skin's immune system helps it regenerate and fight infections.
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April 2019 in “PLOS genetics” CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
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January 2019 in “International Journal of Women's Dermatology” The document concluded that more research is needed to find the best treatment for Frontal fibrosing alopecia.
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August 2003 in “Journal of the European Academy of Dermatology and Venereology” cGVHD often severely affects the skin, causing rapid aging and other issues.
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September 2012 in “Dermatologic Clinics” Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
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August 1999 in “Journal of Investigative Dermatology” New mutations in hair keratin genes cause the rare hair disorder monilethrix.
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January 2024 in “Journal of Investigative Dermatology” Corticosteroids can reduce scarring in acne keloidalis by targeting specific cells.
22 citations
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March 2023 in “Bioengineering” Stem cell therapies may help improve symptoms and quality of life for people with epidermolysis bullosa.
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March 2021 in “Materials Today Bio” Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.
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April 2017 in “Journal of Investigative Dermatology” Non-coding RNAs are crucial for skin development and health.
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January 2023 in “International Journal of Molecular Sciences” S100A6 protein is linked to disease progression, especially in cancers.
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January 2013 in “Frontiers in Neuroanatomy” Zebrafish can help study and develop treatments for hearing loss.
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October 2022 in “Biomedicines” Regenerative treatments for vitiligo show promise but need more research for long-term safety and effectiveness.
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January 2018 in “Advances in experimental medicine and biology” Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.
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March 2016 in “Cosmetics” Telogen Effluvium is a condition causing excessive hair loss due to stress, illness, drugs, or hormonal changes, and can be treated with specific products or naturally resolves after 3-4 years.
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July 2024 in “Current Issues in Molecular Biology” Understanding molecular processes in skin development is key to creating targeted treatments for skin disorders.
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September 2002 in “Journal of Biological Chemistry” Abnormal keratin expression in mice causes severe oral issues, affecting feeding.
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September 2019 in “Clinical, Cosmetic and Investigational Dermatology” Early treatment of EPDS can improve outcomes and reduce recurrence risk.
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May 2023 in “EMBO reports” High mTORC1 activity slows hair growth and causes it to lose color.
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February 2021 in “PLoS biology” Corin helps control salt and sweat release in sweat glands.
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July 2022 in “Cell reports” Sox2 controls hair color by affecting pigment production in hair follicles.
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March 2022 in “Frontiers in Immunology” Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.
8 citations
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March 2004 in “Mammalian genome” KAP genes are crucial for hair development and show both shared and unique traits in humans, chimpanzees, and baboons.