6 citations
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October 2022 in “Journal of cell science” Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.
5 citations
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January 2017 in “Molecular Medicine Reports” Human hair follicle cells can be turned into neural stem cell-like cells, which might help treat brain diseases.
2 citations
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December 2003 in “Medical electron microscopy” The skin and mucous membranes can regenerate over the basement membrane after damage, using nearby surviving cells.
1 citations
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July 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.
November 2013 in “Elsevier eBooks” Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
September 2016 in “Journal of dermatological science” Adult skin cells can be used to create new hair in a lab.
300 citations
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August 2012 in “Seminars in Cell & Developmental Biology” The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
106 citations
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March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
84 citations
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January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Skin stem cells help maintain skin health, grow hair, and heal wounds.
69 citations
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August 1999 in “Developmental biology” The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
54 citations
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January 2009 in “British Journal of Dermatology” Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.
27 citations
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April 2011 in “Folia Histochemica et Cytobiologica” DHT deficiency can disrupt cell connections in rat testes, possibly affecting fertility.
14 citations
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February 2021 in “Experimental Dermatology” Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.
April 2018 in “Journal of Investigative Dermatology” The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.
August 2021 in “Annals of pathology and laboratory medicine” Most skin tumors in the study were benign, with squamous cell carcinoma being the most common malignant type.
102 citations
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August 2008 in “Genes & Development” Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
42 citations
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March 2008 in “Molecular and Cellular Endocrinology” Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
18 citations
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January 2019 in “Experimental Dermatology” Certain cells outside the hair follicle's bulge area can quickly regenerate damaged hair follicles, potentially helping to reduce hair loss from cancer treatments.
22 citations
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August 2014 in “Clinical endocrinology” Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.
21 citations
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September 2001 in “Graefes Archive for Clinical and Experimental Ophthalmology” Minoxidil may help prevent capsular opacification after cataract surgery.
6 citations
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May 2021 in “Stem Cell Reviews and Reports” Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
438 citations
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October 2010 in “Oncogene” Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
4 citations
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November 2024 in “Cell Biology and Toxicology” Blocking certain receptors in the lungs might help treat a specific type of asthma.
January 1998 in “KAGAKU TO SEIBUTSU” The document suggests that male hormones likely affect hair growth and baldness, and future treatments might involve stem cells and androgen-independent cells.
419 citations
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March 2005 in “Proceedings of the National Academy of Sciences” Hair-follicle stem cells can become neurons.
165 citations
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June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
90 citations
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October 1996 in “Dermatologic Clinics” Growth factors are crucial for hair development and could help treat hair diseases.
90 citations
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January 1979 in “International review of cytology” Wool follicles are complex, involving interactions between different cell types and structures.