April 2019 in “Journal of Investigative Dermatology” Y27632 increases cell growth through EGFR signaling, not ROCK1/2.
52 citations
,
January 2023 in “Annual Review of Immunology” Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.
1 citations
,
January 2020 in “Microscopy research” Researchers successfully grew hair follicle stem cells from mice and humans, which could be useful for tissue engineering and regenerative medicine.
August 2024 in “International Journal of Basic & Clinical Pharmacology” Secretome-based therapies could improve hair growth better than current treatments.
May 2023 in “International Journal of Molecular Sciences” Mesenchymal stem cells could help treat radiation-induced bladder damage but more research is needed to overcome current limitations.
10 citations
,
April 2020 in “PloS one” Lack of Crif1 in hair follicle stem cells slows down hair growth in mice.
53 citations
,
April 2014 in “Experimental Dermatology” Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.
6 citations
,
April 2022 in “Advanced Pharmaceutical Bulletin” Cefazolin-loaded nanoparticles in nanofibers can help heal wounds and support regeneration.
4 citations
,
September 2024 in “Development” Researchers converted human embryonic stem cells into trophoblast stem cells using specific transcription factors.
71 citations
,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
Equine hoof progenitor cells can help develop therapies for hoof diseases like laminitis.
April 2024 in “Cell death and differentiation” Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
56 citations
,
March 2015 in “Cell death and differentiation” Older skin has higher cancer risk due to inflammation and stem cell issues.
41 citations
,
July 1994 in “Journal of Dermatological Science” Hair follicle cells need complex interactions to fully differentiate.
May 2023 in “Frontiers in Cell and Developmental Biology” The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
46 citations
,
September 2023 in “Cell Reports” Sebaceous glands can regenerate after injury using stem cells from hair follicles.
25 citations
,
August 2007 in “Molecular Therapy” Researchers found a safe and effective way to pick genetically modified skin cells with high growth potential using CD24.
7 citations
,
May 2020 in “Trends in molecular medicine” The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
5 citations
,
January 2023 in “Nature cell biology” A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.
35 citations
,
June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
October 2020 in “Stem cells” The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.
85 citations
,
October 2006 in “Current opinion in cell biology” Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.
1 citations
,
March 2019 in “International Journal of Molecular Medicine” Mouse hair follicle cells can become heart-like cells without genetic changes.
8 citations
,
August 2025 in “Journal of Translational Medicine” CD44 signaling can help heal wounds without scars.
October 2023 in “Journal of Cosmetic Dermatology” A synthetic octapeptide may help promote hair growth and counteract hair loss.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” GATA6 is important for maintaining and differentiating cells in a key area of human skin.
11 citations
,
January 2025 in “Regenerative Therapy” Tissue-engineered scaffolds help heal difficult wounds by supporting cell growth and repair.
38 citations
,
July 2019 in “Nature Communications” Par3 protein is essential for skin cell balance and stability.
24 citations
,
September 2023 in “Science Advances” Mettl3 is essential for normal tissue development and self-renewal by regulating gene expression.
4 citations
,
January 2013 in “International Journal of Trichology” Desmogleins are crucial for hair structure and growth.