research Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles
Human hair follicles can provide stem cells for regenerative medicine.
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300-330 / 1000+ resultsresearch Hair Follicle Pigmentation
Hair color is determined by melanin produced and transferred in hair follicles.
research Update on Melasma—Part I: Pathogenesis
Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
research Molecular Mechanisms Regulating Hair Follicle Development
Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
research Immunology of the Human Nail Apparatus: The Nail Matrix Is a Site of Relative Immune Privilege
The nail matrix has a reduced immune response, protecting it from autoimmunity.
research Editorial: Hair Follicle Stem Cell Regeneration in Aging
Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.
research Sox13 is a novel early marker for hair follicle development
Sox13 is a useful marker for early hair follicle development but not essential for hair growth.
research Developmentally regulated expression of integrin alpha-6 distinguishes neural crest derivatives in the skin
Integrin α6 helps identify different neural crest cell types in the skin.
research Toward Elucidating Epigenetic and Metabolic Regulation of Stem Cell Lineage Plasticity in Skin Aging
Epigenetic and metabolic changes affect stem cell function and aging in skin.
research Deciphering the molecular mechanisms of stem cell dynamics in hair follicle regeneration
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
research Recent Advances in the Pathogenesis of Autoimmune Hair Loss Disease Alopecia Areata
Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.
research Gene expression profiling gets to the root of human hair follicle stem cells
Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
research Transcriptome Sequencing Reveals Differences between Primary and Secondary Hair Follicle-derived Dermal Papilla Cells of the Cashmere Goat (Capra hircus)
Primary and secondary hair follicle cells in Cashmere goats have different gene expressions affecting hair growth and size.
research Hydra and the hair follicle – An unconventional comparative biology approach to exploring the human holobiont
Hydra can help understand human hair follicle microbiomes and develop new skin disease therapies.
research Characters of KRT80 and its roles in neoplasms diseases
KRT80 may worsen cancer by increasing growth and spread, but its full effects on treatment and outcomes need more research.
research Logic-based modeling and drug repurposing for the prediction of novel therapeutic targets and combination regimens against E2F1-driven melanoma progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research Introduction to JID Symposium Proceedings 52nd Annual Montagna Symposium on the Biology of Skin “Stem Cells in Skin” Held at Snowmass, Colorado, USA, June 13–17, 2003
Adult somatic stem cells could be used for future skin therapies.
research Pathogenesis and regenerative therapy in vitiligo and alopecia areata: focus on hair follicle
Hair follicles are key to treating vitiligo and alopecia areata, but challenges exist.
research Three Streams for the Mechanism of Hair Graying
Hair graying may be caused by stem cell depletion from stress or melanocyte damage.
research Vasoactive Intestinal Peptide Operates as a Negative Regulator of Human Hair Follicle Pigmentation Ex Vivo
VIP reduces hair pigmentation by decreasing melanin production.
research Stem cell niche: from concept to reality
Stem cell niches are crucial for maintaining stem cells, with Paneth cells and TGF-beta playing key roles.
research Human Hair Graying Revisited: Principles, Misconceptions, and Key Research Frontiers
Hair graying is caused by damage and cell depletion but might be temporarily reversible with drugs and hormones.
research Vitamin A in Skin and Hair: An Update
Vitamin A is important for healthy skin and hair, influencing hair growth and skin healing, but UV light reduces its levels.
research Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome
Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.
research Unraveling the ECM-Immune Cell Crosstalk in Skin Diseases
Abnormal ECM and immune cell interactions can cause skin diseases.
research Expression of Peroxisome Proliferator Activated Receptors (PPARs) in Human Hair Follicles and PPARα Involvement in Hair Growth
PPAR alpha may help in hair growth and could be a target for treatment.
research Neuregulin3 alters cell fate in the epidermis and mammary gland
Neuregulin3 affects cell development in the skin and mammary glands.
research Mettl3-catalyzed m 6 A regulates histone modifier and modification expression in self-renewing somatic tissue
Mettl3 is essential for normal tissue development and self-renewal by regulating gene expression.
research Advances in Microengineered Platforms for Skin Research
Skin-on-a-chip devices better mimic human skin for research.
research Sox2 in the dermal papilla regulates hair follicle pigmentation
Sox2 controls hair color by affecting pigment production in hair follicles.