research Loss of ERBB2 and ERBB3 Receptors Impacts Epidermal Differentiation in Mice
Losing both ERBB2 and ERBB3 receptors in mice causes significant skin problems and inflammation.
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research Distinct tooth regeneration systems deploy a conserved battery of genes
Different fish use the same genes to regrow teeth.
research p63: a crucial player in epithelial stemness regulation
p63 is essential for controlling epithelial stem cells and tissue health.
research Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening
The Spherical Skin Model improves drug and cosmetic testing by accurately mimicking human skin for efficient compound screening.
research An efficient method for isolation of hair papillae and follicle epithelium from human scalp specimens
A new method helps isolate key hair components to study hair growth and loss.
research Immunohistochemical staining characteristics of epidermal appendages (hair follicles and eccrine sweat glands) to anti-epidermal keratin antisera
Hair follicles and sweat glands show different keratin staining patterns.
research Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency
Fatp4 is crucial for healthy skin development and function.
research “Sebocytes’ makeup” - Novel mechanisms and concepts in the physiology of the human sebaceous glands
Hormones and signaling pathways control sebaceous gland function and could help treat acne.
research Cooperation of TGF ‐β and FGF signalling pathways in skin development
TGF-β and FGF pathways are crucial for skin development and regeneration.
research Immunofluorescent localization of collagen types I, III and IV, fibronectin, laminin, and basement membrane proteoglycan in developing mouse skin
research Smart Bio-Polymeric Matrix for Accelerated Wound Healing and Tissue Regeneration
The material combining eggshell protein and scaffold helps wounds heal faster and regenerates tissue effectively.
research Inherited disorders of the skin in human and mouse: from development to differentiation.
Research on skin disorders in humans and mice has improved understanding of hair and skin development.
research 655 In vitro cultivation of dermal-epidermal composites in a single medium supports human hair follicle neogenesis in xenografts
A single medium, PRIME AIRLIFT, supports better human hair follicle formation in grafts.
research The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
research eLife assessment: Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis
Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.
research Cytokeratin expression of apocrine and eccrine poromas with special reference to its expression in cuticular cells
Poromas are related to sweat duct cells, and CK patterns help distinguish apocrine poromas from other neoplasms.
research Hair follicle-derived epithelial sheet has potential in vitiligo treatment
Hair follicle-derived sheets can effectively treat vitiligo by repigmenting skin.
research Ultrastructural characteristics of trichilemmal cysts: report of two cases
Trichilemmal cysts may form from hair follicle outer root sheath growth.
research Tooth tissue and organ regeneration using stem cells
Stem cell-based therapies can regenerate and replace teeth effectively.
research Keratinocytes regulate the function of melanocytes
Keratinocytes control how melanocytes work.
research No evidence for follicular keratinocyte hyperproliferation in acne lesions as compared to autologous healthy hair follicles
Acne lesions don't show increased keratinocyte growth compared to healthy hair follicles.
research Organotypic Skin Culture
Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.
research Bioengineering skin using mechanisms of regeneration and repair
Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
research Decision letter: Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin
ERK activation spreads between cells in mouse skin, linked to cell division and influenced by TPA and EGF receptors.
research The development of an in vitro human hair follicle organoid with a complexity similar to that in vivo
Scientists created a lab-grown hair follicle model that behaves like real hair and could improve hair loss treatment research.
research The role of tight junctions in skin barrier function and dermal absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
research Three-dimensional model of normal human dermal tissue using serial tissue sections
A detailed 3D model of human skin was created to help develop artificial skin.
research Progenitor-derived endothelin controls dermal sheath contraction for hair follicle regression
A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.
research Pseudoepitheliomatous Hyperplasia in Lichen Sclerosus of the Vulva
PEH in vulvar LS is common and needs careful diagnosis to avoid confusion with cancer.
research Epigen Transgenic Mice Develop Enlarged Sebaceous Glands
Overexpressing the epigen gene in mice leads to enlarged sebaceous glands and greasy fur.