April 2020 in “Indian Journal of Forensic Medicine & Toxicology” Laparoscopic ovarian drilling improves menstrual cycles, hormone levels, and pregnancy rates in women with PCOS.
January 2020 in “Dermatology Review” Early diagnosis and treatment are crucial for managing alopecia areata, morphea, and psoriasis.
October 2013 in “Journal of the American College of Cardiology” Higher aldosterone levels in urine are linked to a nondipper blood pressure pattern in healthy people.
October 2013 in “Journal of the American College of Cardiology” Blood pressure that doesn't drop at night is linked to worse blood vessel function in people with high blood pressure.
October 2013 in “Journal of the American College of Cardiology” People with non-dipper hypertension have higher aldosterone levels, more strain on their heart's venous system, and increased risk of endothelial dysfunction.
October 2013 in “Journal of the American College of Cardiology” Hair loss in young adults is linked to harder arteries.
June 2020 in “Aesthetic Surgery Journal” Estradiol-rich plasma can increase hair density faster and more effectively in male pattern baldness treatment than regular plasma.
301 citations
,
May 1998 in “Genes & Development” Ets2 gene is crucial for placental development in mice.
192 citations
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January 2015 in “Journal of the American Academy of Dermatology” Targeted cancer therapies often cause serious skin problems that need careful management.
150 citations
,
April 2013 in “Dermato-endocrinology” Estrogen therapy can reduce skin aging but has cancer risks.
147 citations
,
September 2006 in “Developmental Cell” Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.
130 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).
120 citations
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October 2007 in “Clinical Interventions in Aging” Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.
68 citations
,
April 2014 in “Journal of Molecular Endocrinology” The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.
62 citations
,
January 2003 in “Dermatology” Sunlight worsens hair loss; protect scalp.
58 citations
,
March 2020 in “Scientific Reports” EGFR-TKIs can cause significant skin, nail, and organ side effects.
46 citations
,
March 2013 in “Journal of Cosmetic and Laser Therapy” Non-ablative and ablative fractional lasers helped hair growth in some cases without major side effects, but didn't work for all hair disorders.
43 citations
,
August 2016 in “Scientific Reports” Cinnamomi cortex may help treat prostate enlargement by reducing related proteins.
38 citations
,
February 2012 in “Supportive Care in Cancer” Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
33 citations
,
September 2016 in “Lasers in Surgery and Medicine” Fractional resurfacing is safe and effective for certain skin conditions in Asian patients, but care must be taken to avoid skin pigmentation issues.
32 citations
,
June 2012 in “PLoS ONE” Blocking IL-8 can reduce skin rashes from cancer treatment.
32 citations
,
January 2012 in “International Journal of Dermatology” Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.
31 citations
,
April 2010 in “British journal of dermatology/British journal of dermatology, Supplement” Frontal fibrosing alopecia can cause sudden hair loss on limbs, similar to scalp hair loss.
26 citations
,
May 2015 in “Lasers in Surgery and Medicine” Laser treatment helped regrow hair in mice by activating a key growth pathway.
25 citations
,
September 2018 in “Molecular Biology of the Cell” Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
24 citations
,
November 2017 in “Aesthetic Plastic Surgery” All types of Platelet-Rich Plasma (PRP) can treat hair loss, but homologous PRP works best due to its higher platelet count and growth factors from multiple donors.
23 citations
,
April 2002 in “Journal of the American Academy of Dermatology” Depigmented hair regrowth after alopecia areata can be permanent.
21 citations
,
January 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.
20 citations
,
April 2011 in “Dermatologic Surgery” Laser therapy helped new hair grow in scarred skin for three patients.
19 citations
,
October 2011 in “Clinics in Dermatology” New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.