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17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

miR-22 helps skin cancer grow and spread by activating specific cell signals.

A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.

Involucrin gene expression is controlled by specific proteins and signaling pathways.

KRT14 gene variants cause dermatopathia pigmentosa reticularis, affecting nails, teeth, and hair.

Some prostate cancers have gene changes that may affect treatment with certain drugs.

Increased methylation of the Filip1l gene may contribute to aggressive skin cancer.

The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.

Stress can cause a type of hair loss in mice lacking the CCHCR1 gene.

The ID2 gene can help distinguish between sensitizers and irritants in skin cells.

Atopic dermatitis shows a link between skin layers in inflammation, detectable with detailed gene analysis.

New mutations in the SLC39A4 gene found in twins help understand the genetic cause of acrodermatitis enteropathica.

A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.

CTHRC1 is essential for healing and preventing heart rupture after a heart attack.

Androgens may influence bladder cancer progression by affecting cellular behavior.

High levels of ODC and a mutant Ha-ras gene cause tumors in mice.

CTCF protein is essential for skin and hair follicle development in mice.

Blocking certain proteins in mouse skin can reduce and shrink skin tumors.

Certain genetic markers can indicate a person's risk of developing prostate cancer.

There's no significant link between the D19S884 marker at the insulin receptor gene and polycystic ovary syndrome.

Two new mutations in the AR gene linked to severe androgen insensitivity were found.

Increased TEMRA cells can predict treatment outcomes in rapidly progressive alopecia areata.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

Certain changes in the VEGF gene can increase or decrease the risk of polycystic ovary syndrome.

High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.