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Overexpression of PKCepsilon leads to increased TNFalpha, promoting metastatic squamous cell carcinoma in mice.

Involucrin is a useful marker for keratinocyte differentiation in mice.

K6 gene expression can be controlled and manipulated in mice for studying skin disorders.

A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.

EGFRi/MEKi treatments cause hair follicles to lose some immune protection, leading to inflammation.

Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.

RANKL improves the immune response against herpes simplex virus by enhancing T cell activation and could help develop better treatments or vaccines.

A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.

Activating CB1 can reduce keratin levels, potentially helping manage psoriasis and aid wound healing.

JAK1 inhibitors can help reduce itchiness in atopic dermatitis.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Keratin 19 expression in certain skin cells is temporary and not a reliable stem cell marker.

Mutations in the KLHL24 gene cause skin blistering in epidermolysis bullosa simplex.

ATR12-351 ointment safely delivers LEKTI protein to the skin, reducing enzyme activity in Netherton syndrome.

Nucleic acids trigger chemokine production in skin cells, affecting skin inflammation.

EBV infection increases a specific keratin variant in carcinoma cells, possibly affecting cell structure and cancer progression.

AMPK activation may reduce melanoma risk in red-haired individuals.

Different types of cells in the eye express specific keratins at various stages of development.

Psoriasis patients' immune response to a hair protein depends on their specific gene type.

The mK6irs1/Krt2-6g gene likely causes wavy hair in mice.

Igf1r helps regulate hair growth cycles.

KSR1 is crucial for certain skin tumor formation and could be a cancer therapy target.

Keratin-75 is secreted by ameloblasts in a unique way without a signal peptide.

A gene mutation causes monilethrix in a Chinese family.

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

TRPV3 channels are involved in skin processes and are affected by shear stress, influencing itch and mechanotransduction.

LEKTI is crucial for skin barrier and immune function, affecting conditions like Netherton syndrome and atopic dermatitis.

Ber‐EP4 marks cells related to the secondary hair germ in hair follicles.

RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.