60 citations
,
September 2010 in “Journal of the American Academy of Dermatology” Small white dots on the scalp seen with a dermoscope correspond to sweat ducts and vary with different hair disorders.
58 citations
,
January 2010 in “Arthritis Care & Research” Hydroxychloroquine may help delay skin damage in lupus patients.
58 citations
,
October 2001 in “Dermatologic Clinics” Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.
54 citations
,
April 2011 in “Journal of Multidisciplinary Healthcare” SLE patients often face depression and anxiety due to physical changes, with African-American and Hispanic patients having higher unmet psychological needs.
54 citations
,
November 2007 in “Actas Dermo-Sifiliográficas” Early diagnosis of frontal fibrosing alopecia is crucial to prevent permanent hair loss.
53 citations
,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.
52 citations
,
March 2010 in “British Journal of Dermatology” Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.
50 citations
,
March 1992 in “PubMed” Malnutrition causes skin changes due to nutrient deficiencies.
48 citations
,
September 2020 in “Frontiers in Immunology” Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.
44 citations
,
April 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
43 citations
,
February 2019 in “International immunology” Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.
42 citations
,
January 2008 in “SKINmed/Skinmed” The article explains how to diagnose and manage certain types of scarring hair loss.
42 citations
,
January 1998 in “BioDrugs” Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
41 citations
,
June 2010 in “Clinics in Dermatology” Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.
40 citations
,
October 2012 in “Journal of the American Academy of Dermatology” CLASI is a valid tool for assessing skin activity and damage in lupus patients.
39 citations
,
July 2008 in “Dermatologic Therapy” Pseudopelade of Brocq is a unique hair loss condition, but its cause and development are still not fully understood.
39 citations
,
March 1976 in “British Journal of Dermatology” Intralesional steroid therapy is useful for treating various skin conditions.
37 citations
,
May 1999 in “Australasian Journal of Dermatology” Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.
37 citations
,
March 1998 in “Lupus” Aggressive SLE treatment helped hair regrowth and improved oral plaque, but scalp lesions stayed.
35 citations
,
February 2023 in “Biomolecules” Granzyme B is important in autoimmune skin diseases and could be a new treatment target.
35 citations
,
October 2012 in “Dermatologic Clinics” Autoimmune diseases can cause hair loss, and early treatment is important to prevent permanent damage.
34 citations
,
April 2016 in “International Journal of Dermatology” Trichoscopy is a useful method for identifying primary cicatricial alopecias and their specific types.
34 citations
,
June 2014 in “The BMJ” Pregnancy can change skin disease severity, with some conditions improving and others worsening, and treatment should balance benefits and fetal safety.
34 citations
,
October 2007 in “International Journal of Dermatology” The most common causes of hair loss in children in South-East Nigeria are fungal infections and alopecia areata.
33 citations
,
December 2014 in “Journal of the European Academy of Dermatology and Venereology” Lichen planus is linked to several autoimmune diseases.
33 citations
,
April 2012 in “British Journal of Dermatology” Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.
32 citations
,
December 2018 in “Cytokine” Type I interferons play a key role in the development of various skin diseases.
28 citations
,
November 2017 in “Skin appendage disorders” The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.
28 citations
,
January 2014 in “Indian Journal of Dermatology, Venereology and Leprology” Chinese patients with primary cicatricial alopecia often have folliculitis decalvans, benefit from treatment, but may experience relapse, with dermoscopy being a useful diagnostic tool.
28 citations
,
April 2009 in “Annals of laboratory medicine” The dense fine speckled pattern in ANA tests is common in autoimmune diseases, challenging previous beliefs that it was unrelated.