20 citations
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January 2017 in “Experimental Dermatology” Igf1r helps regulate hair growth cycles.
Lhx2 is essential for effective Sonic Hedgehog signaling in early retinal development.
Lhx2 helps retinal cells respond to signals for eye development.
127 citations
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July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
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November 2002 in “Journal of Investigative Dermatology” Estrogen receptor α controls hair growth cycles and skin thickness in male mice.
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February 2023 in “Transgenic Research” The E2 protein affects gene activity in hair follicles of mice.
January 1993 in “Claves de razón práctica” ROR2 is crucial for hair follicle stem cell maintenance and self-renewal.
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May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” ELL is crucial for gene transcription related to skin cell growth.
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June 2004 in “Työväentutkimus Vuosikirja” Ectodermal dysplasia syndromes are caused by disruptions in key signaling pathways affecting tooth and hair development.
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July 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” BLMP-1 is important for regular molting and gene expression cycles in worms.
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October 2018 in “BMC genomics” Key genes can rewire networks, changing skin appendage types.
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July 2011 in “PubMed” TRPS1 is crucial for bone, kidney, and hair follicle development.
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September 2007 in “BMC developmental biology” Neuregulin3 affects cell development in the skin and mammary glands.
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June 2019 in “The journal of immunology/The Journal of immunology” A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.
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January 2022 in “Current topics in developmental biology/Current Topics in Developmental Biology” November 2025 in “Indian Journal of Dermatology” Early diagnosis and multidisciplinary care are crucial for improving the quality of life in patients with ectodermal dysplasia.
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January 2012 in “Developmental Biology” EGFR signaling is essential for ear cell regeneration in both birds and mammals.
April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Sweat gland development involves two unique skin cell programs and a temporary skin environment.
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September 2016 in “World Rabbit Science” High wool density in Rex rabbits is linked to specific gene activity affecting hair follicle development.
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August 2019 in “General and Comparative Endocrinology” Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.
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December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Sox9 levels in brain stem cells affect whether they stay as stem cells or become neurons.
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April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
December 2004 in “Differentiation”
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April 2013 in “Stem cells” LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.
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July 2022 in “Genes” Increasing EGR1 levels makes hair root cells grow faster.
April 2018 in “Journal of Investigative Dermatology” The study found that p63 needs signals from morphogens to help skin cells differentiate properly.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Elf5 is important for skin stem cell growth and could help treat skin and hair problems.
June 2011 in “Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)” Estrogens and androgens are crucial for male fertility.
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September 2016 in “EMBO journal” PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.
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October 2023 in “Philosophical Transactions of the Royal Society B Biological Sciences” Different PADI isoforms help cells develop diverse functions.