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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.

The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.

Androgen therapy might help some women with low libido, but it has risks and should be used carefully.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Finasteride helps reduce heart issues and improves heart function.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Some breast cancer patients developed permanent hair loss after chemotherapy and hormonal therapy, showing patterns similar to common baldness and alopecia areata.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Finasteride improves heart function and repairs damage after heart attack in mice.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.

Both steroids, especially cyproterone acetate, harm quail's vital organs.

High-dose radioactive iodine therapy does not harm fertility in thyroidectomy patients.

PRP therapy may help with ovarian issues and fertility, but more research is needed.

Radiotherapy can cause skin fibrosis, which is often overlooked and needs better treatment and evaluation.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Careful medical care is needed for those over 50 on hormone therapy during COVID-19.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.