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Screening for the NUDT15 gene variant can prevent severe side effects from thiopurine drugs in East-Asian people.

Overexpressing ATF3 in mice's epithelial cells may lead to oral cancer.

OXI1 kinase is essential for plant defense and root hair growth in Arabidopsis.

Enzyme replacement therapy may help alleviate symptoms in complex cases like this.

Croton membranaceus root extract can change how drugs are processed in the body.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

HOTTIP and miR-10b contribute to glioma therapy resistance by affecting cell behavior, suggesting they could be targets for treatment.

Combining irinotecan and cetuximab is effective for some metastatic colorectal cancer patients but often causes manageable skin issues.

[6]-Gingerdiol 3-monoacetate shows promise for treating T. whipplei infections.

Ethosomes are a promising way to deliver drugs through the skin.

Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.

Flutamide emulgel with 1% Transcutol P absorbs better through the skin than other mixtures.

Human TMEM2 does not break down hyaluronan but helps control its metabolism.

Molybdenum oxide nanozymes can effectively treat and monitor acute kidney injury by reducing oxidative stress.

Certain genetic variations in OCT1 may improve insulin sensitivity with metformin in women with PCOS.

Electron Beam Tomography (EBT) is a useful additional test to stress testing for detecting heart disease.

TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.

TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.

The two finasteride tablets are bioequivalent.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Human bone cells mainly produce a type 1 enzyme that may help regulate bone health.

Docetaxel is effective against various cancers but mainly causes neutropenia.

Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.

Some people have a genetic variation that makes them less effective at breaking down drugs.

Transglutaminase 2 may control sebocyte maturation and lipid metabolism.

Teprotumumab for thyroid eye disease commonly causes fatigue, brittle nails, dry eyes, hair loss, muscle spasms, and dry mouth, with rare serious events like blood clots.

Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.

A new genetic mutation linked to CARASIL syndrome and small artery disease was found in a Chinese family.