research 709 Nitric oxide-releasing topical therapeutic agent for atopic dermatitis
SB414 may be an effective treatment for atopic dermatitis by reducing swelling and bacterial infection.
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research The Dynamic Duo: Niche/Stem Cell Interdependency
Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.
research TERT/BMI1-transgenic human dermal papilla cells enhance murine hair follicle formation in vivo
Adding TERT and BMI1 to certain skin cells can improve their ability to create hair follicles in mice.
research Oil-in-Water型ナノエマルションに基づく局所経皮送達システムに関する研究
The nanoemulsion system effectively delivers drugs through the skin and shows promise for treating skin conditions.
research Exosomes for repair, regeneration and rejuvenation
Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
research The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice
Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.
research Development, Optimization, and In Vitro/In Vivo Evaluation of Azelaic Acid Transethosomal Gel for Antidermatophyte Activity
Azelaic acid in a special gel is more effective against skin fungi than regular azelaic acid.
research SPT6 maintains epidermal homeostasis by inhibiting an NF-κB-positive feedback loop to prevent excessive inflammation
SPT6 prevents excessive skin inflammation by blocking a feedback loop.
research Phytochemicals as emerging therapeutic agents for alopecia treatment
Plant-based chemicals may help hair growth and prevent hair loss but need more research to compete with current treatments.
research Adipose stem cells from type 2 diabetic mice exhibit therapeutic potential in wound healing
Fat stem cells from diabetic mice can still help heal wounds.
research Adenovirus-Mediated Wnt5a Expression Inhibits the Telogen-To-Anagen Transition of Hair Follicles in Mice
Increasing Wnt5a in mice skin delays hair growth but doesn't stop it.
research In That Issue: Proceedings From the Third Intercontinental Meeting of Hair Research Societies
The meeting covered advances in understanding hair growth, causes of hair loss, and potential treatments.
research Stem Cell-Based Tissue Engineering for the Treatment of Burn Wounds: A Systematic Review of Preclinical Studies
Stem cell treatments may improve burn wound healing.
research Local heroes or villains: tissue-resident memory T cells in human health and disease
Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
research Dynamic Signals for Hair Follicle Development and Regeneration
Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
research Therapeutic Potential of Patient iPSC-Derived iMelanocytes in Autologous Transplantation
Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
research Angiogenin is expressed in human dermal papilla cells and stimulates hair growth
Angiogenin helps hair grow by stimulating cell growth and blood vessel formation.
research A comprehensive review of biochemical factors in herbs and their constituent compounds in experimental studies on alopecia
Herbs might help with hair loss, but more research is needed to confirm their safety and effectiveness.
research Leucine-Rich Repeat-Containing G-Protein-Coupled Receptors as Markers of Adult Stem Cells
Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
research Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib
A patient with Alopecia Areata had complete hair regrowth after using the drug baricitinib.
research Influence of TRPV3 mutation on hair growth cycle in mice
The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.
research Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling
Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
research MoS2 Nanoclusters-based biomaterials for disease- impaired wound therapy
The SA-MS hydrogel is a promising material for improving wound healing and skin regeneration in diseases like diabetes and skin cancer.
research Combined Physicochemical and Transcriptomic Analyses Reveal the Effect of Black Wolfberry Ferment on Alopecia
Black wolfberry ferment may help regrow hair in cases of androgenetic alopecia.
research Flutamide-Loaded Zein Nanocapsule Hydrogel, a Promising Dermal Delivery System for Pilosebaceous Unit Disorders
The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
research Improving the anti-ageing activity of coenzyme Q10 through protransfersome-loaded emulgel
The method improved CoQ10's stability and effectiveness for anti-ageing skincare.
research Transfollicular drug delivery—Is it a reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.
research Group IID, IIE, IIF and III secreted phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Optimization, characterization, and follicular targeting assessment of tretinoin and bicalutamide loaded niosomes
The niosomes effectively target hair follicles for acne treatment.
research Stem Cell Heterogeneity and Plasticity in Epithelia
Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.