research Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride
Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.
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research Modulation of glucocorticoid action and the treatment of type-2 diabetes
Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
research LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.
LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
research Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition
Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.
research Intravaginal Testosterone Improves Sexual Satisfaction and Vaginal Symptoms Associated With Aromatase Inhibitors
Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.
research Testosterone therapy in women: Myths and misconceptions
Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.
research Vitamin D receptor polymorphisms and the polycystic ovary syndrome: A systematic review
The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.
research The Use of Photodynamic Therapy for Treatment of Acne Vulgaris
Photodynamic Therapy is an effective treatment for mild to severe acne.
research The Biological Effects of a Pulsed Electrostatic Field with Specific Reference to Hair Electrotrichogenesis
A pulsed electrical field safely and effectively increased hair growth.
research Herbal Extracts Induce Dermal Papilla Cell Proliferation of Human Hair Follicles
Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.
research Getting under the skin of hair aging: the impact of the hair follicle environment
Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
research Finasteride delays the onset of maternal behavior in primigravid rats
Finasteride slows down motherly behavior in first-time pregnant rats.
research Ovarian morphology is associated with insulin resistance in women with polycystic ovary syndrome: a cross sectional study
Larger ovarian size is linked to higher insulin resistance in women with PCOS.
research Pharmacokinetics of a transdermal testosterone cream in healthy postmenopausal women
A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.
research The probable destructive mechanisms behind COVID-19 on male reproduction system and fertility
COVID-19 may harm male fertility and damage the reproductive system.
research Inhibition of 5α Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice
Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
research In vitro selective inhibition of human UDP-glucuronosyltransferase (UGT) 1A4 by finasteride, and prediction of in vivo drug–drug interactions
Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.
research Protective cardiovascular and renal actions of vitamin D and estrogen
Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.
research Utilizing Electromagnetic Radiation for Hair Growth
Low-Level Laser Therapy and other light treatments for hair growth lack strong evidence and need more research.
research Overexpression of Lnk in the Ovaries Is Involved in Insulin Resistance in Women With Polycystic Ovary Syndrome
Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.
research Polycystic ovary syndrome
The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.
research Persistent Poor Metabolic Profile in Postmenopausal Women With Ovarian Hyperandrogenism After Testosterone Level Normalization
Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.
research Effect of finasteride particle size reduction on its pharmacokinetic, tissue distribution and cellular permeation.
Smaller finasteride particles increase effectiveness in treating hair loss.
research Lisinopril-Induced Alopecia: A Case Report
Lisinopril, a heart medication, probably caused hair loss in a patient, which stopped after switching drugs.
research Treatment of hyperandrogenism in women
Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.
research Pharmacokinetic-pharmacodynamic modeling approach for dose prediction of the optimal long-acting injectable formulation of finasteride
Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.
research Macular Abnormalities Associated With 5α-Reductase Inhibitor
Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.
research Cardiovascular disease risk in women with hyperandrogenism, oligomenorrhea/menstrual irregularity or polycystic ovaries (components of polycystic ovary syndrome): a systematic review and meta-analysis
Women with irregular periods have a higher risk of heart disease.
research Menopause
The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.
research Compendium of polycystic ovarian syndrome and its relevance in glycation and diabetes
PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.