November 2025 in “Eurasian journal of applied biotechnology” Mesenchymal stem cell-derived exosomes show promise for treating skin and tissue diseases.
82 citations
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March 2012 in “Development” Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
January 2012 in “ScholarlyCommons (University of Pennsylvania)” miRNAs are crucial for hair growth and skin health.
4 citations
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February 2021 in “Nano select” MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
16 citations
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April 2022 in “PLoS ONE” Certain microRNAs found in normal cells can effectively suppress various cancers.
63 citations
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January 2021 in “Adipocyte” Adipose tissue-derived exosomes help regulate metabolism and may aid in disease treatment.
April 2026 in “Dermatologic Clinics” 9 citations
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August 2019 in “Journal of the American Academy of Dermatology” Exosomes from stem cells may help treat hair loss.
July 2025 in “Current Stem Cell Research & Therapy” MSC-Exo are safe and effective for treating skin diseases.
1 citations
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July 2024 in “Journal of Associated Medical Sciences” Exosomes from stem cells can help heal and repair tissues.
July 2025 in “International Journal of Pharmaceutical Research and Development” Exosomes can improve skin treatments with fewer side effects.
July 2025 in “Zagazig University Medical Journal” Exosomes can be used for diagnosing and treating skin conditions and improving skin health.
January 2018 in “Contributions to management science” MicroRNAs are crucial for skin development, regeneration, and disease treatment.
28 citations
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August 2019 in “BMC Genetics” miR-148a and miR-10a affect hair growth in Hu sheep.
1 citations
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January 2010 in “Journal of Bioscience and Bioengineering” Exosomes may offer new treatments for hair loss.
123 citations
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November 2012 in “Stem cells” MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.
April 2026 in “Journal of Cosmetic Dermatology” Microneedling with exosomes shows promise for skin issues, but more research is needed.
June 2026 in “Frontiers in Cell and Developmental Biology” The document discusses the role of micro-RNAs (miRNAs) in hair follicle regeneration, highlighting their ability to regulate cell fate transitions, signaling pathways, and inflammatory processes. miRNAs are identified as potential targets for hair regenerative therapies due to their influence on hair follicle stem cell activation and immune microenvironmental homeostasis. The review explores miRNA-mediated pathways such as Wnt/β-catenin and Sonic hedgehog for promoting hair growth, and TGF-β/BMP for initiating hair regression. It also addresses miRNA's role in immune-mediated alopecias like alopecia areata. Delivery strategies for miRNA therapies include lipid nanoparticles and polymeric nanocarriers, but challenges such as off-target effects and immunogenicity remain. The review proposes a roadmap for clinical translation focusing on combinatorial nucleic-acid strategies and standardized efficacy endpoints.
April 2023 in “Research Square (Research Square)” Exosomes protect ear hair cells from damage by controlling cell waste removal, potentially helping treat hearing loss.
49 citations
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May 2020 in “Journal of Clinical Investigation” Exosomes are crucial for protecting sensory hair cells in the inner ear.
January 2026 in “SSRN Electronic Journal”
September 2017 in “Journal of Investigative Dermatology” Certain miRNAs might be involved in a hair loss condition called frontal fibrosing alopecia and could possibly help in its diagnosis.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Dermal papilla cell-derived exosomes can help stem cells grow hair.
August 2023 in “Research Square (Research Square)” Two microRNAs affect hair follicle development in sheep by targeting specific genes.
1 citations
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January 2022 in “Biocell” Exosomes from mesenchymal stem cells show promise for tissue repair but face challenges in isolation and safety testing.
July 2025 in “Journal of Dermatology Research Reviews & Reports” Exosomes show promise as effective treatments for autoimmune skin diseases with fewer side effects.
August 2016 in “Journal of Investigative Dermatology” The research found that certain microRNAs are important for human hair growth and health.
April 2026 in “Frontiers in Cell and Developmental Biology” Exosomes from stem cells can rejuvenate the scalp and improve hair growth.
10 citations
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January 2024 in “Journal of Cosmetic Dermatology” Exosomes have potential in skin treatments but need more research and are only used topically in the U.S.
June 2025 in “International Journal of Dermatology” Exosomes could transform skin treatments but face technical and regulatory hurdles.