April 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Certain small molecules can help regrow hair by turning on the body's cell cleanup process.
December 2017 in “Springer eBooks” Transplant patients often get skin problems, with treatments varying by condition.
October 2016 in “Elsevier eBooks” Common noncancerous skin diseases have various treatments, including topical applications, light therapy, surgery, and medications, with psychological support being important.
September 2015 in “Philippine Journal of Internal Medicine” Recognizing and treating overlap syndrome in connective tissue diseases is crucial.
April 2015 in “Journal of Evolution of Medical and Dental Sciences” People with autoimmune skin diseases often have hearing problems and should get their hearing checked early.
Alopecia areata is an autoimmune disease affecting hair follicles and may harm heart health.
Different connective tissue disorders have unique symptoms and treatments, with varying outcomes and often require ongoing care from a specialist.
January 2014 in “Durham e-Theses (Durham University)” Notch1 helps skin heal by attracting cells that aid repair.
Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.
December 2013 in “Research Portal (King's College London)” Hair loss in Lichen Planopilaris is caused by immune system issues damaging hair follicles and stem cells.
April 2003 in “Experimental Dermatology” The workshop highlighted the genetic links and psychological impacts of hair loss and skin disorders.
July 2008 in “British Journal of Dermatology” Cyclosporin doesn't stop hair loss.
40 citations
,
November 2021 in “npj Regenerative Medicine” Adult spiny mice recover better from heart attacks than common lab mice.
759 citations
,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
403 citations
,
November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
291 citations
,
April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
264 citations
,
January 2008 in “Journal of biomedical optics” Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.
223 citations
,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
187 citations
,
December 2005 in “Experimental Dermatology” Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
179 citations
,
October 2018 in “American Journal of Clinical Dermatology” Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.
158 citations
,
August 2011 in “Reviews in endocrine and metabolic disorders” Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
156 citations
,
August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
124 citations
,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
108 citations
,
July 2002 in “Molecular and cellular biology” Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
85 citations
,
September 2013 in “International Journal of Molecular Sciences” Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
76 citations
,
August 2018 in “International Journal of Cosmetic Science” Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
71 citations
,
February 2006 in “Clinics in Dermatology” Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.
70 citations
,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
64 citations
,
August 2019 in “Circulation” ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.
62 citations
,
October 2017 in “JAMA facial plastic surgery” Condensed nanofat with fat grafts effectively improves atrophic facial scars.