106 citations
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October 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
20 citations
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May 1985 in “British journal of nutrition” Dietary essential fatty acids improved skin and hair conditions and partially corrected fat composition in diabetic mice.
7 citations
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February 2018 in “International Journal of Pharmaceutics” Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.
150 citations
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August 1992 in “Genes & Development” TNF alpha in skin cells causes weight loss, hair and fat issues, and skin inflammation in mice.
2 citations
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April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
282 citations
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April 2007 in “Journal of Agricultural and Food Chemistry” Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.
18 citations
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January 2000 in “Food Science and Technology Research” Apple polyphenols, especially from unripe apples, can help prevent cells from turning into fat cells.
18 citations
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August 2014 in “Lipids” Human hair has more unsaturated fats inside than on the surface, and certain lipids may help bind the outer and inner layers together.
January 2026 in “Journal of Cosmetic Dermatology” Menopause reduces skin fat, but treatments like magnolol and PLLA-SCA can help restore skin health.
2 citations
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September 2022 in “Cytotherapy” Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.
1 citations
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July 2023 in “International Journal of Molecular Sciences” Treating fat stem cells with low oxygen boosts hair growth cell growth through specific signaling pathways.
March 2026 in “Adipocyte” Spt4 and Spt6 are essential for fat cell development.
September 2023 in “The FASEB journal” Foxn1 is important for fat development, metabolism, and wound healing in skin.
3 citations
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December 2007 in “Journal of Otology” Guinea pig fat stem cells can become hair cell-like cells in a lab.
November 2023 in “Cell Proliferation” A protein from fat-derived stem cells, DKK1, is linked to hair loss and blocking it may help treat alopecia areata.
Mealworm protein helps fat cell development and may aid in metabolic health and hair growth.
30 citations
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October 2014 in “Experimental Dermatology” Leptin from skin fat can slow hair growth during certain phases.
22 citations
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April 2017 in “Cell Stem Cell” Skin wounds can create fat cells that help regenerate hair follicles, with BMP signaling playing a crucial role in this process.
16 citations
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February 2013 in “Molecular Medicine Reports” CD34+ cells from fat tissue help form hair follicles and blood vessels in skin.
13 citations
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August 2021 in “Frontiers in Bioengineering and Biotechnology” Exosomes from fat stem cells can reduce fat cell formation.
1 citations
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July 2021 in “Journal of Skin and Sexually Transmitted Diseases” Lipedema is a painful fat disorder in women that's hard to treat, often worsens with hormonal changes, and requires symptom-focused therapies.
September 2023 in “Stem Cells International” Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.
February 2021 in “International journal of regenerative medicine” A new method using fat tissue cells may help treat hair loss.
24 citations
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May 2022 in “Frontiers in Endocrinology” Activating brown fat may help manage PCOS symptoms.
3 citations
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October 2024 in “International Journal of Molecular Sciences” Certain genes in fat tissue affect weight loss in women with PCOS.
September 2025 in “Development” Nelfb is crucial for forming skin fat tissue by regulating genes needed for fat cell development.
12 citations
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January 2022 in “Cells” Dermal papilla cell vesicles can boost hair growth genes in fat stem cells.
6 citations
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March 2024 in “Experimental Dermatology” Fibrosis causes loss of important fat cells, affecting tissue function.
3 citations
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July 2024 in “Cell Proliferation” Blocking TGFβ can help treat fibrotic skin conditions by promoting fat cell formation.
November 2025 in “Scientia Pharmaceutica” Injectable biostimulators can improve skin by boosting collagen and fat cell activity, but more research is needed to confirm their safety and effectiveness.