67 citations
,
February 1997 in “Teratology” Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.
380 citations
,
February 2023 in “Journal of Clinical Medicine” PCOS is influenced by various factors and may be managed by restoring gut health and using new therapies.
72 citations
,
July 2022 in “Frontiers in Systems Biology” Modern lifestyles harm beneficial microbes, affecting health.
5 citations
,
September 2022 in “Frontiers in Nutrition” Gut bacteria differences may help diagnose and treat Alopecia areata.
3 citations
,
January 2021 in “Actas Dermo-Sifiliográficas” The document concludes that changing the scalp's microbiome might be a new way to treat hair loss.
2 citations
,
February 2024 in “International journal of molecular sciences” Gut health affects skin diseases, and probiotics might help.
2 citations
,
May 2022 in “Cosmetics” Further research is needed to understand how the microbiome affects hair loss in Alopecia Areata.
2 citations
,
May 2021 in “Scientific Reports” Stress is likely causing hair loss in Formosan macaques.
August 2025 in “Archiv Euromedica” Gut microbiota changes might play a role in alopecia areata, and microbiome-targeted treatments show promise.
Changes in gut and skin bacteria are linked to different hair loss conditions, and treatments like fecal transplants and probiotics might help, but more research is needed.
March 2021 in “Actas Dermo-Sifiliográficas” The microbiome may be linked to hair loss and could be a target for new treatments.
March 2021 in “Research Square (Research Square)” Stress likely causes hair loss in Formosan macaques.
April 2019 in “Journal of Investigative Dermatology” Alopecia Areata patients have too many Firmicutes and too few Bacteroides in their gut.
2152 citations
,
November 2013 in “Urologia Internationalis” Many men under 40 with erectile dysfunction have organic causes like vascular issues, medication side effects, or hormonal problems.
724 citations
,
April 2004 in “Lancet Oncology” Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.
169 citations
,
September 2002 in “British journal of dermatology/British journal of dermatology, Supplement” ZD1839 (Iressa) causes skin and hair side effects, treatable with tretinoin cream and minocycline.
85 citations
,
August 2015 in “Journal of Applied Genetics” Mutations in specific genes disrupt development of sweat glands, teeth, hair, skin, and nails in HED.
81 citations
,
May 2007 in “Fertility and Sterility” Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
79 citations
,
June 1991 in “Journal of Medical Genetics” X-linked mental retardation includes various syndromes with both mental and physical abnormalities.
78 citations
,
August 2002 in “Experimental Dermatology” Researchers developed a quick and easy way to get and grow cells from the base of human hair follicles.
70 citations
,
November 1984 in “Cell & tissue research/Cell and tissue research” Vitamin D3 affects cell differentiation in specific skin areas.
64 citations
,
August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
59 citations
,
January 2021 in “Genes” Twelve key genes may improve cashmere production by influencing hair follicle cycles.
58 citations
,
February 2021 in “Toxins” Botulinum toxins effectively treat excessive sweating and may help with other skin conditions, but more research is needed.
58 citations
,
December 1992 in “British Journal of Dermatology” Rat hair follicles grow longer in vitro, but certain factors can inhibit this growth.
54 citations
,
July 2017 in “Scientific Reports” JMJD3 and NF-κB activate Notch1, which is essential for skin cell movement and wound healing.
53 citations
,
July 2011 in “Biomaterials” Human liver cells stick to hair protein materials mainly through the liver's asialoglycoprotein receptor.
47 citations
,
October 2015 in “Dermatologic surgery” The 308-nm excimer laser is effective for skin conditions but needs more research on long-term effects.
47 citations
,
April 1978 in “Journal of Cutaneous Pathology” Basal cell epithelioma resembles fetal hair follicles, not adult or fetal skin.
42 citations
,
April 2016 in “Plastic and reconstructive surgery/PSEF CD journals” The hydrogel with fractionated PRP improves skin regeneration by enhancing wound healing and growth of skin structures.