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Gender-affirming hormone therapy improves mental health and gender incongruence but requires careful management of cardiovascular and cancer risks.

Balancing hormones can help women feel youthful and healthy.

Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.

Females with 5 alpha-reductase-2 deficiency have less body hair, no acne, normal fertility, and delayed menarche.

Masculinization in affected individuals occurs gradually after puberty due to hormone changes.

Mouse genital development depends on male or female hormones for specific features.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

A woman developed male characteristics after using unregulated hormone therapy.

Gender-affirming hormone therapy and surgery affect gut bacteria differently.

Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Masculinizing hormone therapy increases the risk of hair loss in transgender and gender-diverse patients.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

Hair restoration helps transgender patients achieve desired gender appearances.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Anti-androgen drugs can treat conditions like prostate cancer and male pattern baldness by blocking effects of testosterone and DHT.

Finasteride helps treat hair loss and prostate issues by blocking a hormone.

Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.

Estrogens can reduce DHT production in hair follicles, but are less effective than finasteride and progesterone.

Male and female mice have different skin thickness, and hormones affect their skin and hair growth differently.