Targeting the PGI2 pathway may help heal diabetic foot ulcers.
57 citations
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August 2006 in “Journal of the American Academy of Dermatology” Gefitinib can cause hair loss without scarring.
13 citations
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March 2020 in “Genes” Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.
2 citations
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October 2024 in “Indian Journal of Orthopaedics”
44 citations
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March 2015 in “PLOS ONE” Fibroblast Growth Factor-9 (FGF-9) can help improve heart function in diabetic mice after a heart attack by reducing inflammation and harmful changes to the heart's structure.
April 2026 in “Journal of Dermatological Treatment” CGF and i-PRF are more effective and safer than PRP for treating female pattern hair loss.
January 2020 in “Global dermatology” Iontophoresis with a growth factor cocktail helps hair growth in patients with androgenetic alopecia.
April 2018 in “Journal of Investigative Dermatology” Fgf20 is important for the development and regulation of the cells that form the base of hair follicles.
4 citations
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January 2015 in “Journal of drug assessment” Finasteride gel effectively and safely reduces hair thickness in women with excessive hair growth.
4 citations
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March 2007 in “British Journal of Dermatology” Gefitinib therapy can cause unusual hair growth on the nose.
November 2005 in “Reactions Weekly” A man treated with gefitinib for lung cancer grew new hair on his bald scalp.
60 citations
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April 2003 in “Biomaterials” Controlled release of growth factors in hydrogels improved hair growth in mice.
28 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology”
45 citations
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July 2009 in “Journal of human genetics” A gene variation is linked to hair thickness in Asians.
2 citations
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September 2002 in “Journal of Endocrinological Investigation” The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.
39 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” FGF and EGF are crucial for hair follicle development and growth.
3 citations
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December 2024 in “Journal of Animal Physiology and Animal Nutrition” FGF20 is essential for hair follicle stem cell growth and development in fine-wool sheep.
23 citations
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March 2019 in “Gene” Editing the FGF5 gene in sheep increases wool length, confirming its role in hair growth.
119 citations
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November 2014 in “Trends in Cell Biology” Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.
17 citations
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December 2010 in “Journal of Investigative Dermatology” Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.
Compound 6 is a promising candidate for better wound healing.
42 citations
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September 2015 in “Gene” FGF5s can block the effects of FGF5, which may help control hair growth in cashmere goats.
1 citations
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September 2023 in “Baghdad Journal of Biochemistry and Applied Biological Sciences” The mFG score is effective for diagnosing hirsutism.
252 citations
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March 1998 in “Developmental dynamics” FGFs-4, -8, and -9 have overlapping roles and are repeatedly used in tooth development.
7 citations
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March 2022 in “International Journal of Molecular Sciences” FGF21 can help reduce skin inflammation caused by C. acnes.
January 2016 in “프로그램북(구 초록집)” The growth factor cocktail with FGF9 significantly increased hair density and diameter in patients with androgenetic alopecia.
44 citations
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April 2006 in “Expert opinion on drug safety” Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.
Some fibroblast growth factors may promote hair growth similarly to minoxidil and could potentially treat hair loss.
20 citations
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January 2017 in “Scientific reports” Whale genes show changes that help them live in water, like less hair and better flippers.
May 2025 in “Journal of Investigative Medicine” FAI is a better marker for predicting female hair loss than testosterone or SHBG alone.