research Building a Better Scar: Re-engineering Extracellular Matrix Structure in Dermal Scars
αCT1 improves scar appearance by changing early collagen structure.
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870-900 / 1000+ resultsresearch Localization of Type I Human Skin Collagenase in Developing Embryonic and Fetal Skin
research Silk Fibroin‐Based Nanoparticles Blended Fluoridated Hydrogel with Photodynamic Antibacterial for Infected Wound Healing
The new hydrogel dressing effectively kills bacteria and helps wounds heal faster with hair regrowth.
research Extra-follicular cutaneous manifestations of frontal fibrosing alopecia
Recognizing skin symptoms helps diagnose and treat frontal fibrosing alopecia.
research Osteopontin regulatory functions in the hair follicle open a therapeutic approach for hypertrichosis
FOL-005 peptide may help treat excessive hair growth safely.
research Transglutaminase-mediated cross-linking in mammalian epidermis
research Regenerating Hair Follicles
Healing skin wounds in mice can create new hair follicles, and adjusting Wnt signaling could potentially reduce scarring and treat hair loss.
research Sprayable supramolecular hydrogel with minimalism for wilderness first aid: integration of mechanical performance and biofunctionality
The hydrogel speeds up wound healing and fights bacteria, making it great for emergency use.
research Biocomposite nanofiber matrices to support ECM remodeling by human dermal progenitors and enhanced wound closure
The nanofiber scaffolds improved skin wound healing by supporting cell growth and tissue repair.
research Lamprey-Teeth-Inspired Oriented Antibacterial Sericin Microneedles for Infected Wound Healing Improvement
The document explains how to make antibacterial microneedles inspired by lamprey teeth to help heal infected wounds.
research Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair: Wnt1/βcatenin injury response regulates cardiac repair
The Wnt1/βcatenin pathway is crucial for heart repair after injury.
research Editorial highlights
The document highlights recent advances in developmental biology, focusing on three studies. The first study establishes a zebrafish model for Diamond-Blackfan anemia like (DBAL), showing that epoa-deficient zebrafish can be used to screen treatments for anemia, with recombinant human EPO improving erythrocyte numbers. The second study investigates the role of Alx4 in craniofacial and hair development, using Alx4fx/fx conditional mice to explore the mechanisms of ALX4-related disorders and alopecia, finding that Alx4 loss leads to developmental defects and hair loss. The third study examines the mTORC1 signaling pathway's role in retinal development, demonstrating that its disruption in retinal progenitor cells causes lamination deficits and visual behavior loss, highlighting mTORC1's importance in CNS histogenesis.
research Deletion of an enhancer in FGF5 is associated with ectopic expression in goat hair follicles and the cashmere growth phenotype
A genetic change in the FGF5 gene affects hair growth in cashmere goats.
research Autologous Platelet Concentrates: Their Generations, Forms, Preparation Protocols and Roles in Periodontal Regeneration
PRF is preferred for better healing in dental surgeries.
research Comparative Proteomics Indicates That Biosynthesis of Pectic Precursors Is Important for Cotton Fiber and Arabidopsis Root Hair Elongation
Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.
research Female pattern hair loss: beyond an androgenic aetiology?
Estrogen and prolactin may play bigger roles in female hair loss than previously thought.
research Serine Biosynthesis In Human Hair Follicles By The Phosphorylated Pathway: Follicular 3-Phosphoglycerate Dehydrogenase
research Dendritic Cell–Associated MARCKSL1 Regulates Fibroblast Differentiation During Wound Healing
MARCKSL1 is important for wound healing and could be a target to reduce scarring.
research Table 2_Molecular mechanisms underlying cashmere quality differences between Jiangnan cashmere goats and Changthangi pashmina goats.xlsx
Cashmere quality differences between goat breeds are linked to specific genes and pathways.
research Efficacy and Safety of Rb‐bFGF in Hair Transplantation: A Prospective and Comparative Study
Rb-bFGF improves hair transplant results and patient satisfaction with fewer complications.
research Frontal fibrosing alopecia: A review of 60 cases
Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.
research Molecular biology of hair morphogenesis: Development and cycling
Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.
research Unusual patterns of presentation of frontal fibrosing alopecia: A clinical and trichoscopic analysis of 98 patients
Trichoscopy helps diagnose frontal fibrosing alopecia, even with unusual patterns.
research Nanoscale microenvironment engineering for expanding human hair follicle stem cell and revealing their plasticity
A new method was developed to grow and maintain human hair follicle stem cells for hair reconstruction.
research Human Dermal Fibroblasts Demonstrate Positive Immunostaining for Neuron- and Glia- Specific Proteins
Fibroblasts can be mistaken for neural cells, so functional validation is needed.
research Collagenase IV plays an important role in regulating hair cycle by inducing VEGF, IGF-1, and TGF-β expression.
Collagenase IV helps control hair growth by affecting certain growth factors.
research Proteoglycans and Associated Proteins of the Mammalian Hair Follicle
research 3D bioprinting of a gelatin-alginate hydrogel for tissue-engineered hair follicle regeneration
The new 3D bioprinting method successfully regenerated hair follicles and shows promise for treating hair loss.
research Senescence-induced reparative fibroblasts enable scarless wound healing in aged murine skin.
Older mice heal wounds without scars due to special fibroblasts.
research The Molecular Architecture for the Intermediate Filaments of Hardα-Keratin Based on the Superlattice Data Obtained from a Study of Mammals Using Synchrotron Fibre Diffraction
Hard α-keratin has a universal molecular structure with a specific superlattice arrangement.