EGF and FGF signaling stops hair follicle development in mice.
December 1998 in “福井大学教育学部紀要 第4部 教育科学” HA-P5 effectively treats acne without causing side effects seen in other treatments.
Knocking out the FGF5 gene in sheep increased wool production and hair-follicle density.
January 2003 in “Jiefangjun yixue zazhi” Growth factors in skin increase with age, aiding development and healing.
March 2022 in “Molecules” Adenosine can help treat hair loss by promoting hair growth.
August 2013 in “Nature Reviews Drug Discovery” A protein called FGF9 helps regenerate hair follicles in mice after skin damage, and increasing FGF9 could potentially help human hair growth.
9 citations
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January 2018 in “Medical research archives” Low-intensity light therapy is effective for skin healing, reducing inflammation, and treating various skin conditions.
349 citations
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January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
222 citations
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January 2005 in “Endocrine journal” Melatonin is important for skin health and protection, and can be made by the skin or applied to it.
49 citations
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March 2019 in “Journal of Investigative Dermatology” Skin fat plays a key role in immune defense and healing beyond just storing energy.
36 citations
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July 2014 in “Experimental Dermatology” Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.
35 citations
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October 2017 in “Signal Transduction and Targeted Therapy” Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.
24 citations
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October 2017 in “Scientific reports” Changing light exposure can affect hair growth timing in goats, possibly due to a key gene, CSDC2.
21 citations
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January 2023 in “International Journal of Molecular Sciences” S100A6 protein is linked to disease progression, especially in cancers.
15 citations
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March 2022 in “Acta Biomaterialia” The new 3D bioprinting method successfully regenerated hair follicles and shows promise for treating hair loss.
11 citations
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January 1988 in “PubMed” Epidermal cell extracts improve skin healing and reduce scarring.
9 citations
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July 2018 in “Current Pharmaceutical Design” HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
5 citations
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October 2020 in “Bioengineering & translational medicine” Researchers used a laser to create advanced skin models with hair-like structures.
5 citations
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September 2023 in “Journal of Cosmetic Dermatology” c-Maf positive macrophages help form hypertrophic scars by affecting fibroblasts and collagen production.
4 citations
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May 2014 in “Journal of Cutaneous Medicine and Surgery” Platelet-rich plasma may help with wound healing, hair growth, and skin rejuvenation, but more research is needed to prove its effectiveness.
1 citations
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March 2023 in “Colloids and surfaces. B, Biointerfaces” A new wound dressing with p-Coumaric acid helps heal diabetic wounds faster by reducing inflammation and promoting skin repair.
1 citations
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March 2014 in “Applied Microscopy” CK19 and Vimentin are proteins found in rat skin that help with skin renewal and maintaining cell structure.
1 citations
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May 2012 in “International Conference on Biomedical Engineering and Biotechnology” TGF-β receptor 1 helps deer antlers grow by aiding skin and cartilage cell growth.
June 2026 in “Advanced Healthcare Materials” Engineered vesicles with EGF mRNA improve skin wound healing and reduce scarring.
Exosomes show promise for improving skin health and healing.
November 2025 in “Journal of Investigative Dermatology” Mesenchymal stiffness affects sweat gland cell development.
February 2024 in “Skin health and disease” Exosomes could improve skin and hair treatments but are limited by cost, production difficulty, and need for more research.
January 2024 in “AIP conference proceedings” Medicinal plant-based hydrogel films are promising for diabetic wound dressings.
December 2023 in “Animal research and one health” Certain circular RNAs are crucial for wool growth and curvature in goats.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Adipocytes can change into fibroblast-like cells to help with wound healing.