April 2023 in “Journal of Investigative Dermatology” Radiation treatment causes skin fibrosis by increasing certain fibroblast subpopulations, but using a c-Jun inhibitor or fat grafting can reduce this effect.
August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Different types of skin cells create unique support structures that can affect skin cell growth and could help in skin repair.
418 citations
,
January 2018 in “Journal of Investigative Dermatology” Researchers found four distinct fibroblast types in human skin, which could help in treating wounds and fibrotic diseases.
50 citations
,
December 2017 in “British Journal of Dermatology” Different skin cells produce unique materials, which can improve skin substitutes for healing.
September 2021 in “Morphologia” Dermal fibroblasts have at least three distinct types, each with unique roles in skin structure and hair development.
Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
April 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Older mice heal wounds without scars due to special fibroblasts.
42 citations
,
July 2021 in “Frontiers in Cell and Developmental Biology” Oral mucosa heals with minimal scarring, offering insights for scarless wound healing.
1 citations
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August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
2 citations
,
January 2024 in “Proceedings of the National Academy of Sciences of the United States of America” The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
April 2023 in “Journal of Investigative Dermatology” The research shows that skin cancer likely originates from hair follicles and that certain cell populations expand to promote skin cancer growth.
2 citations
,
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Rare Gli1+ fibroblasts are crucial for skin wound healing.
146 citations
,
July 2018 in “Regenerative Medicine” Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.
4 citations
,
June 2022 in “Cold Spring Harbor Perspectives in Biology” Different types of fibroblasts exist in skin and understanding them can help improve wound healing and treat scars.
225 citations
,
April 2018 in “Journal of Investigative Dermatology” Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
35 citations
,
August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
17 citations
,
July 2022 in “Advances in Wound Care” Fibroblasts play a crucial role in the body's response to implants, needing more research for better treatments.
9 citations
,
May 2021 in “Immunological Reviews” Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
Different types of sun exposure can damage skin cells and affect healing, with chronic exposure being more harmful, and certain immune cells help in the repair process.
1 citations
,
July 2025 in “Scientific Reports” CD133+ cells are crucial for hair growth.
5 citations
,
May 2023 in “Frontiers in Cell and Developmental Biology” Integrin α6 helps identify different neural crest cell types in the skin.
54 citations
,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.
September 2016 in “Journal of dermatological science” Human induced pluripotent stem cells can be used to create cells that help grow hair.
822 citations
,
January 2021 in “Genome biology” scMC effectively separates biological signals from technical noise in single-cell genomics data.
5 citations
,
January 2025 in “Burns & Trauma” Machine learning and single-cell analysis improve understanding and treatment of wound healing.
April 2016 in “Journal of Investigative Dermatology” A specific type of immune cells, called CD301b-expressing macrophages, are crucial for skin repair processes.
11 citations
,
January 1988 in “PubMed” Epidermal cell extracts improve skin healing and reduce scarring.
48 citations
,
June 2020 in “Current Rheumatology Reports” Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
301 citations
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February 2019 in “Nature Communications” The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
299 citations
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January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.