6 citations
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October 2019 in “Case Reports in Dermatology” The document concludes that treatment can improve hair growth and symptoms in Fibrosing Alopecia in a Pattern Distribution.
201 citations
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April 2017 in “Regeneration” Macrophages and fibroblasts help repair organs after injury, affecting whether they regenerate or scar.
January 2026 in “Preprints.org” Mimicking fetal wound environments may enable scarless healing in adults.
2 citations
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April 2018 in “Journal of Investigative Dermatology” Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.
179 citations
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December 2004 in “Journal of The American Academy of Dermatology” Some postmenopausal women with frontal fibrosing alopecia stopped losing hair with finasteride treatment, hinting at a possible hormonal cause.
126 citations
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August 2018 in “Molecular Systems Biology” Fibroblast state switching is crucial for skin healing and development.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin heals with scars because only one type of fibroblast is used, not a mix.
January 2026 in “Clinical Cosmetic and Investigational Dermatology” Early diagnosis and targeted anti-inflammatory treatments can improve outcomes in androgenetic alopecia with perifollicular inflammation and fibrosis.
January 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” Early biopsy and targeting inflammation can improve treatment for hair loss in androgenetic alopecia.
5 citations
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October 2019 in “JAAD Case Reports” These hair loss conditions might be part of a spectrum, not separate issues.
April 2017 in “Journal of Investigative Dermatology” HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.
33 citations
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February 2024 in “International Journal of Molecular Sciences” Understanding fibroblast issues in diabetic foot ulcers is key to creating better treatments.
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September 2020 in “Proceedings - Baylor University. Medical Center” Tofacitinib successfully treated a woman's severe symptoms from a rare autoimmune condition.
30 citations
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January 2020 in “Journal of The American Academy of Dermatology” Fibrosing alopecia in a pattern distribution is a hair loss condition often confused with other types, requiring early treatment but usually not resulting in significant hair regrowth.
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January 2009 in “Indian Journal of Dermatology, Venereology and Leprology” A patient with granuloma annulare experienced both isotopic and isomorphic responses, with skin lesions responding to steroids but relapsing after stopping treatment.
20 citations
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August 2022 in “Frontiers in Immunology” Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.
September 2019 in “Journal of Investigative Dermatology” Mouse skin fibroblasts vary in function and adaptability based on their environment.
November 2025 in “Skin Appendage Disorders” Fibrosis contributes to hair loss in androgenetic alopecia, and targeting it may improve treatment.
Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
April 2012 in “Informa Healthcare eBooks” Fibrosing alopecia in a pattern distribution is a unique hair loss condition with inflammation and scarring, resembling but distinct from common balding.
36 citations
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December 2017 in “Journal of the American Academy of Dermatology” Most patients with frontal fibrosing alopecia stabilized with treatment, especially younger ones, using intralesional corticosteroids and tacrolimus.
May 2005 in “Molecular Carcinogenesis” mrp/plf-mRNA can indicate tumor-promoting effects in skin.
February 2025 in “Archives of Dermatological Research” Fibrosing alopecia can be diagnosed without typical signs of lichen planopilaris.
March 2025 in “International Journal of Trichology” FAPD in children may not depend on androgens and should be treated with anti-inflammatory measures and minoxidil.
Combining anti-androgenic, anti-inflammatory, and anti-fibrotic treatments may improve hair loss outcomes.
4 citations
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May 2023 in “Cells” Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.
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July 2019 in “Medicina Clínica (English Edition)” Tofacitinib partially improved hair regrowth in a patient with severe hair loss.
9 citations
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February 2002 in “International Journal of Dermatology” The patient's symptoms improved with treatment but recurred when the steroid dose was reduced, requiring ongoing therapy.
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August 2018 in “The American Journal of Dermatopathology” Researchers found a new early sign of Frontal Fibrosing Alopecia that could help avoid misdiagnosis.
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology”