Advances in RNA research and skin models offer hope for better skin healing without scarring.
April 2026 in “International Journal of Molecular Sciences” Targeting non-Smad pathways in TGF-β signaling may improve keloid treatment.
April 2026 in “Research Square” E13 fetal mouse fibroblast vesicles may help reduce scarring.
April 2026 in “Journal of Investigative Dermatology” Mechanotransduction aids healthy wound healing by promoting specific fibroblasts.
Fraser's Dolphin can heal skin wounds with minimal scarring, unlike humans.
March 2026 in “Wound Repair and Regeneration” MARCKSL1 is important for wound healing and could be a target to reduce scarring.
November 2025 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” Sporadic trichoblastic neoplasms generally don't recur or spread, with one case showing a specific genetic fusion.
July 2025 in “Journal of Investigative Dermatology” Discoid lupus erythematosus involves immune activation and fibrosis around hair follicles, with shared pathways across humans, dogs, and mice, suggesting potential treatments for both humans and animals.
July 2025 in “International Journal of Molecular Sciences” Blocking CXCL12 can reverse hair loss and fibrosis in androgenetic alopecia.
August 2024 in “Life Science Alliance” Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.
Removing SIX1 in fat cells reduces skin fibrosis.
October 2023 in “Skin research and technology” The 675 nm laser effectively improved facial acne scars in dark skin with minimal side effects.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking EGFR can lead to hair loss due to inflammation and stem cell damage.
November 2022 in “PubMed” Deep dermal tissue dislocation injury in pigs leads to thicker fibrotic tissue and increased type III collagen, affecting skin repair.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Male hormones and reduced plakoglobin can impair heart electrical function and increase arrhythmia risk in males.
July 2020 in “Experimental Dermatology” Aging causes hair thinning in women due to changes in the scalp environment.
September 2019 in “Romanian Journal of Pediatrics” Fetal skin can heal without scars, offering insights for better wound treatments.
August 2019 in “Journal of Medical Histology” EMT helps heal tissues but can cause scarring and other issues if prolonged.
January 1998 in “Boletín de la Asociación Andaluza de Bibliotecarios/Boletín de la Asociación Andaluza de Bibliotecarios” ADSC therapy is promising for antiaging skin treatment.
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May 2015 in “Archives of dermatological research” PPAR agonists show promise for skin conditions but need more research before being a main treatment.
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September 2021 in “The FASEB Journal” ACKR2 helps prevent skin scarring and hair loss by controlling inflammation.
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April 2018 in “Journal of Investigative Dermatology” CCCA may be a fibroproliferative disorder, and anti-fibrotic therapies could help.
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May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Rare Gli1+ fibroblasts are crucial for skin wound healing.
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March 2023 in “Pharmaceutics” PBMCsec can help reduce and improve thick skin scars.
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March 2023 in “Science Translational Medicine” Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.
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October 2020 in “The Egyptian Journal of Histology” Ginseng was more effective than finasteride in treating enlarged prostate in rats.
Bee venom can improve various skin conditions, including varicose veins and psoriasis, and has anti-aging benefits.
January 2026 in “Materials Horizons” The hydrogel helps wounds heal without scars and promotes new hair growth.
November 2025 in “Skin Appendage Disorders” Fibrosis contributes to hair loss in androgenetic alopecia, and targeting it may improve treatment.
Combining anti-androgenic, anti-inflammatory, and anti-fibrotic treatments may improve hair loss outcomes.