38 citations
,
February 2019 in “Clinical Interventions in Aging” Dutasteride more effectively treats hair loss than finasteride, but may increase risk of altered libido.
37 citations
,
September 2018 in “Psychoneuroendocrinology” Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.
37 citations
,
February 2009 in “Bioorganic & Medicinal Chemistry” Finasteride complexes with HPβCD and polymers improve solubility, potentially enhancing hair loss treatment.
36 citations
,
June 2014 in “International Journal of Dermatology” Dutasteride helps hair growth in those unresponsive to finasteride, but may cause more sexual dysfunction.
33 citations
,
November 2019 in “Journal of Controlled Release” Microneedles with enhancer effectively promote hair growth and increase hair density.
33 citations
,
December 2015 in “Neuroendocrinology” Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.
33 citations
,
October 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces hair growth and is safe for women with excessive hair.
32 citations
,
April 1999 in “Expert Opinion on Investigational Drugs” Finasteride effectively treats male hair loss, improving growth and density.
30 citations
,
April 2002 in “Archives of Dermatology” Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.
30 citations
,
December 1999 in “International Journal of Dermatology” Finasteride increases hair count in middle-aged and elderly men without causing sexual dysfunction.
29 citations
,
April 1995 in “Endocrinology” Finasteride doesn't affect bone density in male rats.
29 citations
,
April 2004 in “Annals of Pharmacotherapy” Finasteride reduces hirsutism effectively with fewer side effects but is a second-choice treatment due to safety concerns.
28 citations
,
February 1999 in “Archives of Dermatological Research” Finasteride potentially treats hair loss by reducing DHT production.
28 citations
,
January 1991 in “Reproductive Toxicology” Finasteride temporarily lowers male rat fertility without affecting libido.
28 citations
,
December 2003 in “Medical Hypotheses” Ketoconazole shampoo with finasteride improves hair density in men with hair loss.
27 citations
,
June 2013 in “Alcoholism: Clinical and Experimental Research” Finasteride use may lead to less alcohol consumption in men with lasting sexual side effects.
27 citations
,
May 2008 in “Neuroscience” Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.
27 citations
,
January 2001 in “Endocrine Practice” Finasteride cream reduces hair growth in women with hirsutism, but more research needed.
27 citations
,
November 1998 in “Journal of Endocrinological Investigation” Finasteride significantly reduces hair growth in women with idiopathic hirsutism.
26 citations
,
December 2019 in “Neurobiology of Stress” Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.
26 citations
,
July 2014 in “Analytical Chemistry Research” Method can accurately measure five BPH drugs at once.
26 citations
,
July 1995 in “Neurobiology of Aging” Finasteride affects prostate weights and pituitary activity differently with age.
26 citations
,
November 1993 in “Progress in Neuro-psychopharmacology & Biological Psychiatry” Treatment during development affects hormone balance and sexual behavior in male rats.
25 citations
,
September 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.
24 citations
,
October 2008 in “International Braz J Urol” Lovastatin doesn't improve lower urinary tract symptoms treatment.
23 citations
,
June 2014 in “Journal of Pharmaceutical Sciences” Finasteride cream helps hair growth with less side effects.
23 citations
,
January 2002 in “Journal of Cutaneous Medicine and Surgery” Finasteride helps hair growth by decreasing cell death in hair follicles.
23 citations
,
June 1999 in “Clinical Therapeutics” Finasteride is a cost-effective option for treating BPH, reducing risk of urinary issues and surgery.
23 citations
,
April 1999 in “The Journal of Clinical Endocrinology and Metabolism” All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.
21 citations
,
January 2002 in “Journal of Cutaneous Medicine and Surgery” Finasteride affects hair growth by changing caspase and XIAP levels, potentially treating hair diseases.