research Chapter 23. Therapeutic Control of Androgen Action
Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
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research 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro
11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.
research The role of aquaporins in polycystic ovary syndrome – A way towards a novel drug target in PCOS
Aquaporins could be new drug targets for treating polycystic ovary syndrome.
research The impact of biomaterial characteristics on macrophage phenotypes in tissue engineering: a review
Biomaterial characteristics can influence macrophages to promote healing and improve tissue regeneration.
research RoPod, a customizable toolkit for non-invasive root imaging, reveals cell type-specific dynamics of plant autophagy
RoPod helps study plant root cell changes and autophagy with minimal stress.
research iTRAQ-based proteome profiling revealed the role of Phytochrome A in regulating primary metabolism in tomato seedling
Phytochrome A is crucial for normal metabolism and development in tomato seedlings under far-red light.
research Invasomes: Vesicles for Enhanced Skin Delivery of Drugs
Invasomes effectively deliver drugs through the skin and have potential for improved treatments.
research In Vivo Monitoring of Survival and Proliferation of Hair Stem Cells in a Hair Follicle Generation Animal Model
The technique allowed noninvasive tracking of hair stem cell survival and growth, showing potential for hair loss research.
research The Effect of Methylsulfonylmethane on Hair Growth Promotion of Magnesium Ascorbyl Phosphate for the Treatment of Alopecia
Combining MSM with MAP significantly promotes hair growth.
research Plasma Rico em Plaquetas Otimizando o Rejuvenescimento Dérmico nos Procedimentos Estéticos
Platelet-rich plasma (PRP) is a cost-effective way to improve skin rejuvenation and repair in facial aesthetics.
research Effect of Topically Applied Minoxidil on the Survival of Rat Dorsal Skin Flap
Minoxidil applied before and after surgery improves skin flap survival in rats.
research Synergistic Wound Healing: Unraveling the Multi-Target Effects of Traditional Chinese Medicine and Its Biomaterials on Chronic Wound Pathways
Traditional Chinese Medicine and biomaterials help heal chronic wounds by targeting multiple pathways.
research Topical and transdermal lipid-polymer hybrid nanoparticles (LPN): an integration in advancing dermatological treatments
Lipid-polymer hybrid nanoparticles show promise for skin treatments but need better formulation strategies.
research Overexpression of hypoxia-inducible factor-1α in hidradenitis suppurativa: the link between deviated immunity and metabolism
Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.
research Pathophysiological and Pharmaceutical Considerations for Enhancing the Control of Sarcoptes scabiei in Wombats Through Improved Transdermal Drug Delivery
Improving how drugs are absorbed through the skin could better treat mange in wombats.
research Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers
Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.
research Placebo‐controlled dose‐effect studies with topical minoxidil 2% or 5% in male‐patterned hair loss treated with oral finasteride employing an analytical and exhaustive study protocol
Minoxidil 5% works better than 2% for hair growth in male-patterned hair loss.
research Protein kinase C is a key target for attenuation of Leigh syndrome by rapamycin
Rapamycin may help treat Leigh syndrome by targeting protein kinase C.
research Synergistic effect of platelet-rich plasma injections and scalp lifting in androgenetic alopecia
PRP injections and scalp lifting together improve hair thickness and growth in hair loss patients.
research Testicular Steroidogenesis
Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
research The spectrum of nephrocutaneous diseases and associations
Skin doctors should know about skin and kidney disease links to prevent serious kidney problems.
research An efficient method for eccrine gland isolation from human scalp
Scientists developed a way to isolate sweat glands from the scalp during hair transplants, keeping them alive for 6 days for research and cosmetic uses.
research Interventions for central serous chorioretinopathy: a network meta-analysis
No treatment is clearly better for central serous chorioretinopathy, and more research is needed.
research Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice
Increasing neuropeptide Y in the brain can slow aging signs in mice.
research Integrated Transcriptomics and Metabolomics Analyses of Stress-Induced Murine Hair Follicle Growth Inhibition
Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.
research Impairment of autophagy may be associated with follicular miniaturization in androgenetic alopecia by inducing premature catagen
Impaired autophagy may cause hair loss by triggering early catagen.
research Multimodal imaging of hair follicle bulge-derived stem cells in a mouse model of traumatic brain injury
Hair follicle stem cells might help treat traumatic brain injury.
research Imaging prostate cancer (PCa) with [99m Tc(CO)3 ]finasteride dithiocarbamate
A new compound was effective for imaging prostate cancer in rats.
research Integration of Ethylene and Auxin Signaling and the Developmental Consequences of Their Crosstalk
Ethylene and auxin hormones interact in complex ways that are essential for plant growth and development.
research Renal Vitamins
Dialysis patients benefit from water-soluble vitamins but need careful management to avoid risks.