73 citations
,
June 2006 in “Animal genetics” The FGF5 gene determines hair length in dogs.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Early treatment and multidisciplinary care are key to managing Frontal Fibrosing Alopecia and preventing further hair loss.
November 2023 in “Animal Bioscience” miR-133a-3p and miR-145-5p help goat hair follicle stem cells differentiate by controlling NANOG and SOX9.
July 2026 in “Materials Today Bio” The MQ complex helps heal melanoma wounds by controlling ROS levels with light.
61 citations
,
January 2019 in “American Journal of Clinical Dermatology” The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.
July 2019 in “Zenodo (CERN European Organization for Nuclear Research)” Follicular mucinosis in a 15-year-old is usually harmless but needs monitoring for possible lymphoma.
November 2024 in “Actas Dermo-Sifiliográficas” Low-dose oral minoxidil can improve hair and eyebrow growth in frontal fibrosing alopecia.
6 citations
,
December 2024 in “F1000Research” Fibroblast and immune cell interactions affect tissue repair and fibrosis.
1 citations
,
April 2025 in “American Journal of Medical Genetics Part C Seminars in Medical Genetics” Eflornithine improved symptoms in Bachmann–Bupp Syndrome patients.
6 citations
,
June 2019 in “International Journal of Dermatology” Frontal fibrosing alopecia has occurred in two related male families.
May 2021 in “FEBS open bio” July 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” Excessive sun protection might contribute to frontal fibrosing alopecia.
29 citations
,
April 2000 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” ICAM-1 helps regulate hair growth cycles and skin remodeling.
102 citations
,
April 2014 in “International Journal of Dermatology” The treatment helped reduce symptoms and stabilize the hairline in most patients with Frontal Fibrosing Alopecia, but hair regrowth was limited.
32 citations
,
October 2004 in “Experimental Dermatology” α-MSH may help treat skin inflammation and fibrosis.
66 citations
,
December 2014 in “Nature Communications” Fibroblasts can be turned into melanocytes for potential skin treatments.
September 2017 in “Journal of Investigative Dermatology” Thermal imaging is a useful non-invasive method to diagnose active inflammation in frontal fibrosing alopecia.
36 citations
,
December 2017 in “Journal of the American Academy of Dermatology” Most patients with frontal fibrosing alopecia stabilized with treatment, especially younger ones, using intralesional corticosteroids and tacrolimus.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking a key energy pathway in human hair follicles can trigger stress responses that stop cell growth.
71 citations
,
May 1996 in “Journal of Investigative Dermatology” Ornithine decarboxylase is crucial for hair growth regulation in mice.
26 citations
,
June 2003 in “PubMed” Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.
April 2017 in “Journal of Investigative Dermatology” Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.
April 2011 in “The FASEB Journal” Profilin1 speeds up wound healing.
November 2024 in “Journal of Investigative Dermatology” Adrenomedullin 2 stops cell growth and causes cell death in human hair follicles.
15 citations
,
December 2014 in “PLoS ONE” A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
37 citations
,
January 2010 in “Human Molecular Genetics” FTase and GGTase-I are essential for skin keratinocyte health.
25 citations
,
August 2010 in “Journal of Biological Chemistry” Nuclear Factor I-C is important for controlling hair growth by affecting the TGF-β1 pathway.
2 citations
,
December 2021 in “Pharmaceutics” Finasteride-loaded proniosomes effectively promote hair growth in mice.
75 citations
,
September 2007 in “Journal of Heredity” FGF5 gene mutations cause long hair in domestic cats.
September 2024 in “Journal of the American Academy of Dermatology” Phenoxyethanol in hair growth products may be linked to frontal fibrosing alopecia.