research Association of Frailty Index with Clinical BPH Progression and Serious Adverse Events: the MTOPS Trial
Frailer men have a higher risk of worsening prostate problems and serious health events needing hospital care.
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research In vivo reflectance confocal microscopy: usefulness for diagnosing hair diseases
In vivo reflectance confocal microscopy is useful for evaluating hair shaft diseases but needs improvement for deeper hair follicle issues.
research RASopathic Skin Eruptions during Vemurafenib Therapy
Vemurafenib causes skin side effects similar to RASopathies, requiring regular skin checks and UVA protection.
research Is SFRP-4 an early potential biomarker related to diabetes and hypertension, in patients with androgenic alopecia?
SFRP-4 might be an early indicator of diabetes and hypertension in men with androgenic alopecia.
research A novel mutation in Hr causes abnormal hair follicle morphogenesis in hairpoor mouse, an animal model for Marie Unna Hereditary Hypotrichosis
A new mutation in the Hr gene causes hair loss in mice, similar to a human hair disorder.
research Low-Dose Oral Minoxidil Improves Hairline and Eyebrow Coverage in Frontal Fibrosing Alopecia: A Prospective Study
Low-dose oral minoxidil helps improve hairline and eyebrow coverage in frontal fibrosing alopecia.
research Erythema multiforme following topical minoxidil
Minoxidil can cause erythema multiforme, even if patch tests are negative.
research miR-3606-3p alleviates skin fibrosis by integratively suppressing the integrin/FAK, p-AKT/p-ERK, and TGF-β signaling cascades
miR-3606-3p reduces skin fibrosis by blocking key signaling pathways.
research Teriflunomide in multiple sclerosis: an update
Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.
research [Striatal involvement on MRI in adrenomyeloneuropathy].
MRI can show unusual brain changes in adrenomyeloneuropathy.
research Hidradenitis suppurativa and Mediterranean fever gene mutations
Hidradenitis suppurativa may be more severe in people with Mediterranean fever gene mutations.
research AB0597 Comparative analysis of safety data of four treatment regimens in early rheumatoid arthritis patients
Methotrexate plus prednisolone had the fewest serious side effects.
research VIBRATIONAL SPECTROSCOPIC INVESTIGATION AND MOLECULAR STRUCTURE OF A 5α-REDUCTASE INHIBITOR: FINASTERIDE
Finasteride's molecular properties and active sites were identified using computational methods.
research Thermal imaging and dermoscopy for detecting inflammation in frontal fibrosing alopecia
Infrared thermography, especially with dermoscopy, improves accuracy in diagnosing active hair loss due to inflammation.
research TMPRSS2: A Key Host Factor in SARS-CoV-2 Infection and Potential Therapeutic Target
TMPRSS2 is crucial for COVID-19 infection and is a potential target for treatment.
research Specific inhibition of FGF5-induced cell proliferation by RNA aptamers
RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.
research 5 alpha-reductase inhibition by a new synthetic steroid (PM-9) in cultures of Penicillium crustosum.
PM-9, like finasteride, may help treat certain diseases by blocking a key enzyme.
research Development of a portable reflectance confocal microscope and its application in the noninvasive in vivo evaluation of mesenchymal stem cell-promoted cutaneous wound healing
A new portable microscope can effectively monitor skin wound healing in real-time.
research Synchronous profiling and analysis of mRNAs and ncRNAs in the dermal papilla cells from cashmere goats
Non-coding RNAs help control hair growth in cashmere goats.
research Male pattern hair loss - rh79g
research Frontal fibrosing alopecia: reflections and hypotheses on aetiology and pathogenesis
FFA's causes may include environmental triggers and genetic factors.
research Frontal fibrosing alopecia: a disease fascinating for the researcher, disappointing for the clinician and distressing for the patient
Frontal Fibrosing Alopecia is a poorly understood condition that is hard to treat and causes distressing hair loss.
research Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research ECM1 modified HF-MSCs targeting HSC attenuate liver cirrhosis by inhibiting the TGF-β/Smad signaling pathway
ECM1-modified stem cells can effectively treat liver cirrhosis.
research Injectable Platelet‐Rich Fibrin (PRF): The newest biomaterial and its use in various dermatological conditions in our practice: A case series
Injectable Platelet-Rich Fibrin (I-PRF) showed positive results for treating hair loss, skin texture, wrinkles, and wounds.
research FEA-guided co-design of bubble microneedles: controlled tip separation for rapid transdermal and sublingual delivery
This study introduces a finite element analysis (FEA)-guided framework for designing separable bubble microneedles (BMNs) that optimize geometry and cavity parameters for controlled tip separation and robust insertion. The study tested minoxidil sulfate-loaded BMNs (MXS-BMNs) and insulin-loaded BMNs (INS-BMNs) for transdermal and sublingual delivery, respectively. The BMNs demonstrated effective payload release, with over 80% liberated within 10 minutes. In ex vivo tests, MXS-BMNs showed significantly higher minoxidil permeation compared to topical gel, and in vivo tests on mice showed accelerated hair regrowth. INS-BMNs effectively lowered glucose levels in diabetic rats, comparable to subcutaneous injections. This approach reduces empirical iteration, facilitating the development of efficient microneedle systems for rapid drug delivery.
research Cardiovascular Safety Signals of Oral Versus Topical Minoxidil in FAERS: A Disproportionality Analysis (Analytic Cohort 2012–2025)
Oral minoxidil may have more cardiovascular risks than topical minoxidil.
research Immortalized human hair follicle-derived mesenchymal-like stromal cells for the long-term production of scalable Immunomodulatory and regenerative secretome
Immortalized hair follicle cells could be useful for regenerative medicine and treating inflammation and oxidative stress.
research Insights learned from L457(3.43)R, an activating mutant of the human lutropin receptor
The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
research The ‘Watch Sign’ – Another Observation in the Course of Male Frontal Fibrosing Alopecia
Hair loss in male frontal fibrosing alopecia may spare areas covered by a wristwatch.