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Did you mean Hair Follicle Activation?

GlossaryHair Follicle Activation

process of stimulating dormant follicles to promote hair growth

Hair Follicle Activation refers to the process of stimulating dormant or inactive hair follicles to enter the growth phase, known as anagen. This can be achieved through various methods such as topical treatments, laser therapy, or microneedling, which aim to enhance blood flow, nutrient delivery, and cellular activity in the scalp, thereby promoting hair growth.

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research Transient activation of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours

335 citations , March 2004 in “Development”

Temporary activation of β-catenin can create new hair follicles, but ongoing activation is needed to keep hair follicle tumors.

research Hepatocyte growth factor (HGF) activator expressed in hair follicles is involved in in vitro HGF-dependent hair follicle elongation

77 citations , February 2001 in “Journal of Dermatological Science”

HGF activator helps convert HGF to its active form, promoting hair growth.

research Wnt activator CHIR99021-stimulated human dermal papilla spheroids contribute to hair follicle formation and production of reconstituted follicle-enriched human skin

40 citations , June 2019 in “Biochemical and Biophysical Research Communications”

CHIR99021 helps create human skin with hair follicles, offering hope for hair loss treatments.

research STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction

32 citations , April 2016 in “Journal of Investigative Dermatology”

STAT5 activation is crucial for starting the hair growth phase.

Double-Stranded RNA Induces Inflammation via the NF-κB Pathway and Inflammasome Activation in the Outer Root Sheath Cells of Hair Follicles

research Double-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles

22 citations , March 2017 in “Scientific reports”

Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.

Pharmacological Activation of Thermo-Transient Receptor Potential Vanilloid 3 Channels Inhibits Hair Growth by Inducing Cell Death of Hair Follicle Outer Root Sheath

research Pharmacological Activation of Thermo–Transient Receptor Potential Vanilloid 3 Channels Inhibits Hair Growth by Inducing Cell Death of Hair Follicle Outer Root Sheath

12 citations , June 2019 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics”

Activating TRPV3 channels stops hair growth by killing hair follicle cells.

Oral Minoxidil Bio-Activation by Hair Follicle Outer Root Sheath Cell Sulfotransferase Enzymes Predicts Clinical Efficacy in Female Pattern Hair Loss

research Oral minoxidil bio‐activation by hair follicle outer root sheath cell sulfotransferase enzymes predicts clinical efficacy in female pattern hair loss

9 citations , August 2019 in “Journal of The European Academy of Dermatology and Venereology”

Minoxidil activation by hair enzymes predicts treatment success for female hair loss.

Intrinsic Activation of Cell Growth and Differentiation in Ex Vivo Cultured Human Hair Follicles by a Transient Endogenous Production of ROS

research Intrinsic activation of cell growth and differentiation in ex vivo cultured human hair follicles by a transient endogenous production of ROS

9 citations , March 2019 in “Scientific reports”

Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.

Differential Distribution of the Epigenetic Marker 5-Hydroxymethylcytosine in Hair Follicle Stem Cells During Bulge Activation

research Differential distribution of the epigenetic marker 5‐hydroxymethylcytosine occurs in hair follicle stem cells during bulge activation

4 citations , February 2019 in “Journal of Cutaneous Pathology”

The marker 5-hmC changes in hair follicle stem cells when they start to grow.

STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction, Hair Follicle Regeneration, and Wound Healing

research 219 STAT5 activation in the dermal papilla is important for hair follicle growth phase induction, hair follicle regeneration and wound healing

1 citations , August 2016 in “Journal of Investigative Dermatology”

Activating STAT5 in the skin's dermal papilla is key for starting hair growth, regenerating hair follicles, and healing wounds.

research TLR9 activation in large wound induces tissue repair and hair follicle regeneration via γδT cells

August 2024 in “Cell Death and Disease”

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

research TLR9 activation in large wound induces tissue repair and hair follicle regeneration via gamma delta T cells

February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)”

Activating TLR9 helps heal large wounds and regrow hair by involving a specific type of immune cell.

research 1392 Activation of Id2 gene regulatory network ruling quiescence of hair follicle stem cells

April 2018 in “Journal of Investigative Dermatology”

Id2 gene helps keep hair follicle stem cells inactive.

research 668 Activation of Nrf2 promotes wound healing by expansion of hair follicle stem cell populations

September 2017 in “Journal of Investigative Dermatology”

Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.

research Abstract 4300: Constitutive activation of Stat3 increases hair follicle progenitor population at the expense of bulge region keratinocyte stem cells

April 2010 in “Cancer Research”

Stat3 activation increases hair follicle progenitors but reduces bulge region stem cells.

Assessment of Trial to Use Exosomes and Salmon DNA with Minoxidil as Multisource Mixture for Hair Follicle Activation: An In Vivo Study

research Assessment of Trial to Use Exosomes and Salmon DNA with Minoxidil as Multisource Mixture for Hair Follicle Activation an In Vivo Study

March 2025 in “Benha Journal of Applied Sciences”

Combining exosomes, salmon DNA, and minoxidil boosts hair growth more than minoxidil alone.

research Repurposing DPP4-Inhibition to Improve Hair Follicle Activation and Regeneration

May 2023 in “Journal of Investigative Dermatology”

Blocking DPP4 can potentially speed up hair growth and regeneration, especially after injury or in cases of hair loss.

research 755 Repurposing of DPP4 inhibition to improve hair follicle activation and regeneration

July 2022 in “Journal of Investigative Dermatology”

Blocking DPP4 can help activate hair growth and improve hair regeneration.

research Activation of mTORC1 Signaling is Required for Timely Hair Follicle Regeneration from Radiation Injury

12 citations , October 2017 in “Radiation Research”

mTORC1 signaling needed for quick hair follicle recovery after radiation damage.

research Activation of mitochondrial aldehyde dehydrogenase 2 promotes hair growth in human hair follicles

11 citations , November 2023 in “Journal of Advanced Research”

Activating ALDH2 can boost hair growth.

research The incidental pore: Ca_V1.2 and stem cell activation in quiescent hair follicles

3 citations , June 2013 in “Genes & development”

CaV1.2 helps activate hair follicle stem cells without calcium flux.

Traditional Chinese Medicine Shi-Bi-Man Regulates Lactic Acid Metabolism and Drives Hair Follicle Stem Cell Activation to Promote Hair Regeneration

research Traditional Chinese Medicine Shi-Bi-Man regulates lactic acid metabolism and drives hair follicle stem cell activation to promote hair regeneration

1 citations , July 2023 in “Chinese Medicine”

Shi-Bi-Man, a Traditional Chinese Medicine, helps grow hair by boosting lactic acid metabolism and activating hair follicle stem cells.

research Additional file 1 of Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis

January 2024 in “Figshare”

Activating autophagy in hair follicle stem cells can lead to hair growth and repair by affecting sugar metabolism.

research Activation of β-catenin signaling programs embryonic epidermis to hair follicle fate

193 citations , May 2008 in “Development”

Activating β-catenin can turn skin cells into hair follicles.

research Hair Follicle Mesenchyme-Associated PD-L1 Regulates T-Cell Activation Induced Apoptosis: A Potential Mechanism of Immune Privilege

53 citations , September 2013 in “Journal of Investigative Dermatology”

Hair follicle cells help protect against immune attacks by regulating T-cell activity.

research Constitutive Stat3 activation alters behavior of hair follicle stem and progenitor cell populations

23 citations , September 2013 in “Molecular Carcinogenesis”

Increased Stat3 activity reduces hair follicle stem cells and boosts other stem/progenitor cells.

Nuclear Factor (Erythroid-Derived 2)-Like-2 Pathway Modulates Substance P–Induced Human Mast Cell Activation and Degranulation in the Hair Follicle

research Nuclear factor (erythroid-derived 2)-like-2 pathway modulates substance P–induced human mast cell activation and degranulation in the hair follicle

8 citations , May 2018 in “The Journal of Allergy and Clinical Immunology”

Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.

research 495 OR2AT4 activation by a synthetic odorant, stimulates dermcidin production in human hair follicle epithelium and increases follicular resistance to bacterial contamination: A novel antimicrobial folliculitis therapy?

April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

A synthetic sandalwood odorant can boost antimicrobial production in hair follicles, making them more resistant to bacteria.

research 1338 Dermal Wnt/β-catenin activation tunably controls hair follicle initiation

May 2018 in “Journal of Investigative Dermatology”

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

research 1312 Nrf2 activation enhances the healing of cutaneous wounds through the activation of hair follicle stem cells

April 2018 in “Journal of Investigative Dermatology”

Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.