Stem cell treatments show promise for hair loss but need more research.
October 2022 in “MedNEXT Journal of Medical and Health Sciences” PRP effectively treats hair loss, especially when combined with microneedling or minoxidil.
415 citations
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January 2008 in “Cell” NFATc1 controls hair stem cell activity, affecting hair growth and could be a target for hair loss treatments.
214 citations
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April 2017 in “Cell” Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
54 citations
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January 2012 in “Vitamins & Trace Elements” People with Alopecia Areata have lower vitamin D levels.
28 citations
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April 2024 in “Immunity” CD80 on skin stem cells helps expand Treg cells to aid wound healing.
28 citations
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June 2020 in “ACS Biomaterials Science & Engineering” The new ECM patch greatly improves wound healing and tissue regeneration.
7 citations
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December 2018 in “Discoveries” Platelet-rich plasma may improve wound healing by stimulating cell growth and blood vessel formation.
3 citations
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August 2022 in “Molecules/Molecules online/Molecules annual” A new strain of bacteria from the human skin can help prevent hair loss.
2 citations
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May 2024 in “Immunity” Stem cells help control the immune response to improve wound healing.
2 citations
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November 2023 in “Biomolecules” WNT signaling is crucial for skin development and healing.
2 citations
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December 2021 in “Pharmaceutics” Finasteride-loaded proniosomes effectively promote hair growth in mice.
1 citations
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February 2025 in “Journal of Anatomy” Gray short-tailed opossums' skin shifts from helping with breathing to regulating body temperature as they grow.
1 citations
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August 2024 in “Polymers” The P25H5-O microneedles effectively deliver substances through hair follicles and are safe for skin cells.
June 2026 in “Frontiers in Cell and Developmental Biology” LHX2 is crucial for development, tissue repair, and preventing diseases.
January 2026 in “PLoS Biology” ARHGEF3 is essential for proper hair follicle development in mice.
January 2025 in “Biomaterials Research” The new zinc peroxide hydrogel speeds up wound healing and tissue regeneration effectively.
August 2024 in “Receptors” Vitamin D receptor is crucial for skin wound healing.
June 2023 in “Frontiers in Bioengineering and Biotechnology” The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
May 2023 in “Pharmaceuticals” Three specific mutations in the LIPH gene can cause hair loss by damaging the protein's structure and function.
January 2022 in “Clinical Cases in Dermatology” Early treatment of traction alopecia can reverse hair loss; prevention involves avoiding tight hairstyles.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
71 citations
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January 2011 in “Orphanet Journal of Rare Diseases” IFAP syndrome is a rare genetic disorder causing skin, hair, and eye issues, with limited treatment options.
18 citations
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October 2017 in “PLOS ONE” The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.
17 citations
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July 2022 in “BMC Genomics” The FA2H gene improves cashmere fineness by enhancing hair growth in goats.
22 citations
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July 1990 in “Acta Dermato Venereologica” High levels of testosterone and dihydrotestosterone inhibit hair cell growth, while high levels of estradiol promote it.
19 citations
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September 2019 in “PLOS genetics” Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
34 citations
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October 2014 in “European journal of pharmaceutics and biopharmaceutics” The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
12 citations
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June 2022 in “International Journal of Molecular Sciences” Copper boosts cell growth in rabbit hair follicles.
117 citations
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April 2008 in “Developmental biology” Ectodysplasin inhibits Wnt signaling to help form hair follicles.