January 2022 in “Stem cell biology and regenerative medicine” iPSCs could help develop treatments for hair loss.
Bipotent dermal stem cells and specific macrophages are crucial for hair regrowth and regeneration.
184 citations
,
November 2014 in “Developmental Cell” Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.
June 2023 in “Plastic and Reconstructive Surgery” Stem cell therapy from hair follicles effectively treats advanced hair loss with minimal side effects.
January 2017 in “PRISM (University of Calgary)” Unique genes in hair follicle cells help tissue regeneration.
12 citations
,
December 2019 in “International Journal of Molecular Medicine” Stem cells from umbilical cord blood may prevent hair loss caused by certain medications.
37 citations
,
May 2016 in “Scientific Reports” Combining skin cells with fat-derived stem cells can improve hair growth.
26 citations
,
February 2012 in “Journal of Investigative Dermatology” Human hair follicle cells can be successfully transformed into different types of cells, but not more efficiently than other adult cells.
15 citations
,
September 2009 in “European Journal of Histochemistry” CD90 is abundantly present on stem-like cells in dog hair follicles.
3 citations
,
November 2022 in “International journal of molecular sciences” Bio-pulsed stimulation increases production of beneficial vesicles from bird stem cells that improve skin and hair cell functions.
June 2024 in “Regenerative Therapy” iPSCs show promise for hair regeneration but need more research to improve reliability and effectiveness.
Human hair follicle cells can be turned into stem cells that may help clone hair for treating hair loss or burns.
January 2009 in “Journal of Jilin University” 3T3 fibroblasts feeder is best for growing epithelial stem cells from hair follicles.
September 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Scientists successfully created fully functional hair follicles using bioengineering methods and stem cells.
835 citations
,
October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
305 citations
,
June 2012 in “Nature” Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.
242 citations
,
February 2016 in “Science” Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
202 citations
,
August 2017 in “Nature cell biology” Lactate production is important for activating hair growth stem cells.
179 citations
,
April 2012 in “Nature Communications” Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.
175 citations
,
December 2014 in “PLoS Biology” Macrophages help activate hair follicle stem cells, affecting hair growth and skin repair.
144 citations
,
June 2008 in “Cell Cycle” Hair follicle stem cells can help repair spinal cord injuries and improve walking.
142 citations
,
February 2016 in “Science” Foxc1 helps keep hair follicle stem cells inactive, preventing hair loss.
141 citations
,
May 2007 in “Cancer Research” CD34 is crucial for skin tumor development in mice.
133 citations
,
March 1999 in “Journal of Cutaneous Pathology” Trichoepitheliomas and some basal cell carcinomas likely come from hair follicle stem cells.
106 citations
,
March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
98 citations
,
December 2003 in “The FASEB Journal” Thymosin β4 promotes hair growth by activating stem cells in hair follicles.
87 citations
,
February 2004 in “Plastic and Reconstructive Surgery” Hair follicle stem cells helped heal a severe scalp burn without needing traditional skin grafts.
87 citations
,
February 2000 in “Journal of Investigative Dermatology” Stem cells in developing hair follicles move to specific areas as they mature.
86 citations
,
June 2017 in “Stem cell investigation” Stem cells from hair follicles can safely treat hair loss.
85 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology”