387 citations
,
November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
321 citations
,
January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
55 citations
,
September 2003 in “Experimental Dermatology” PDGF signaling may play a role in hair growth cycle regulation.
7 citations
,
May 2022 in “Frontiers in Cell and Developmental Biology” Epigenetic and metabolic changes affect stem cell function and aging in skin.
6 citations
,
July 2015 in “JAAD Case Reports” Doxycycline can effectively treat hair loss caused by EGFR inhibitors.
5 citations
,
September 2021 in “Frontiers in Cell and Developmental Biology” Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.
July 2025 in “International Journal of Trichology” Biological factors are crucial for developing new hair restoration treatments.
154 citations
,
October 1996 in “Proceedings of the National Academy of Sciences of the United States of America” Estrogen affects hair growth and skin cell multiplication.
3 citations
,
March 2023 in “Scientific Reports” Researchers developed a new method to test hair growth drugs and found that adult cells are best for hair growth, but the method needs improvement as it didn't create mature hair follicles.
February 2026 in “Biochemical and Biophysical Research Communications” Scientists successfully regenerated functional hair follicles using specific stem cells and mesenchymal cells.
41 citations
,
October 2008 in “The American journal of pathology” Blocking a specific protein signal can make hair grow on mouse nipples.
169 citations
,
January 2018 in “Cell Reports” Scientists grew hair follicles from mouse stem cells in a lab setting.
10 citations
,
August 2021 in “Frontiers in cell and developmental biology” Scientists made structures that look like human hair follicles using stem cells, which could help grow hair without using actual human tissue.
36 citations
,
April 2016 in “Biochimie” A substance called epidermal growth factor helps increase the growth of important hair follicle cells by activating a specific cell communication route.
13 citations
,
November 2003 in “Humana Press eBooks” ES cells can be turned into hair follicle cells in a lab setting.
3 citations
,
January 2016 in “International Journal of Trichology” Sheep-derived factors improve human hair cell clustering, which may help hair growth.
March 2026 in “The Korean Society for Veterinary Nursing” Eremochloa ophiuroides extracts may effectively promote hair growth like minoxidil.
December 2025 in “Preprints.org” Aging dermal papilla cells can be reprogrammed for potential hair growth and skin repair.
October 2025 in “Journal of Ethnopharmacology” Andrographolide from Andrographis paniculata promotes hair growth and could be a natural treatment for hair loss.
August 2025 in “Biomaterials” A new therapy using secretions from fetal cartilage cells shows promise for safe and effective hair regrowth.
8 citations
,
October 2022 in “Regenerative Therapy” New regenerative treatments for hair loss show promise but need more research for confirmation.
1398 citations
,
May 2008 in “Histochemistry and Cell Biology” Keratins are crucial for cell stability, wound healing, and cancer diagnosis.
35 citations
,
January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
29 citations
,
May 2020 in “npj Regenerative Medicine” Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
16 citations
,
July 2008 in “BMC Genomics” Alpha 6 + /MHCI - cells have stem cell traits and are similar to mouse hair follicle stem cells.
15 citations
,
July 2013 in “Cell Reports” Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.
13 citations
,
June 2007 in “Journal of Dermatological Science” Researchers created a cell line to study hair growth and found specific genes affected by dihydrotestosterone.
7 citations
,
August 2021 in “Heliyon” Phyllotex™ extract was found to significantly promote hair growth and protect against hair loss.
June 2025 in “International Journal of Molecular Sciences” Targeting EMT and fibrotic remodeling may help treat androgenetic alopecia.
January 2019 in “Advances in stem cells and their niches” Krox20 is important for cell differentiation in the brain and hair follicles.