12 citations
,
November 2012 in “BioMolecular Concepts” PPAR β/δ is important for skin health and disease treatment, but more research is needed.
8 citations
,
June 2022 in “Cosmetics” Coffee berry extract may help slow skin aging and prevent hair loss.
January 2026 in “Dermatologic Therapy” Human foreskin fibroblast–conditioned medium improved hair growth in androgenetic alopecia patients.
February 2025 in “Applied Sciences” Scenedesmus deserticola JD052 extracts may help hair growth and could be a natural treatment for hair loss.
March 2024 in “Stem cell research & therapy” Human dental pulp stem cell-conditioned medium, especially from hypoxic conditions, may help treat chemotherapy-induced hair loss and does not increase cancer risk.
172 citations
,
July 2007 in “Journal of Dermatological Science” Stat3 helps skin heal but can also cause skin diseases if overactive.
52 citations
,
February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
51 citations
,
March 2022 in “Frontiers in Immunology” Alarmin cytokines are key in controlling skin immunity and inflammation.
40 citations
,
May 2005 in “Journal of Cell Science” Truncated LTBP-1 disrupts TGF-β signaling, affecting hair growth.
35 citations
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December 2014 in “Lasers in surgery and medicine” Red light promotes hair growth by directly stimulating hair cells and improving cell communication.
30 citations
,
November 2020 in “Journal of Advanced Research” Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.
30 citations
,
February 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Plet-1 protein helps hair follicle cells move and stick to tissues.
26 citations
,
January 2007 in “Organogenesis” Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.
16 citations
,
August 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” MED1 is essential for normal hair growth and maintaining hair follicle stem cells.
13 citations
,
April 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
13 citations
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January 2018 in “Yonsei Medical Journal” A specific gene mutation causes Olmsted syndrome.
12 citations
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January 2018 in “PubMed” Y-27632 helps hair follicle stem cells grow and keep their abilities.
9 citations
,
February 2001 in “Journal of Dermatological Science” p21waf1/cip1 and p27kip1 help in hair follicle differentiation in rats.
8 citations
,
March 2009 in “Differentiation” Adult vibrissa follicle stem cells can regenerate hair follicles, glands, and skin.
2 citations
,
August 2023 in “Autophagy” Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.
March 2026 in “Journal of Nanobiotechnology” A new microneedle treatment can effectively repigment skin in vitiligo.
December 2025 in “Biomedicines” Tyrosine kinase inhibitors for endocrine tumors often cause skin issues, requiring early management and treatment adjustments.
April 2024 in “Molecules/Molecules online/Molecules annual” Paris polyphylla saponins may effectively treat acne due to their antibacterial and anti-inflammatory properties.
Glypican-1 is important for hair follicle blood vessel growth and could be a target for treating hair loss.
19 citations
,
September 2008 in “Journal of Cellular Physiology” Blocking EGFR can cause skin inflammation by disrupting IL-1 signaling.
September 2023 in “JPRAS Open” Botulinum Toxin A may help with hair growth and has some side effects; more research is needed.
January 2022 in “Stem cell biology and regenerative medicine” Improving dermal papilla cells can help regenerate hair follicles.
57 citations
,
November 1998 in “Wound Repair and Regeneration” Hair papilla cells can create and regenerate hair bulbs under the right conditions.
24 citations
,
July 1983 in “Clinical and Experimental Dermatology” Tigason improved hair growth in a boy with monilethrix without side effects.
21 citations
,
June 2017 in “Case Reports in Dermatology” Reducing gefitinib dosage improved hair loss, but scarring remained.