January 2024 in “Dermatologic therapy” AKN is a chronic scalp condition in African-descended males, treated with topicals, antibiotics, steroids, and sometimes surgery or laser.
January 2024 in “Skin appendage disorders” Using growth factors and microneedling shows promise for hair regrowth in Alopecia Areata, but more research is needed.
21 citations
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July 2015 in “International Journal of Nanomedicine” Increased liposome fluidity boosts skin penetration of sodium fluorescein.
December 2023 in “Biological & pharmaceutical bulletin” IPM enhances skin penetration of hydrophilic drugs.
September 2025 in “Journal of Drug Delivery Science and Technology” Vitamin D3-coated nanoparticles effectively deliver caffeine for alopecia treatment with minimal side effects.
10 citations
,
January 2014 in “Journal of Pharmaceutical Sciences” Balancing lipophilicity and solubility is key for effective and safe ketorolac prodrugs.
10 citations
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April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.
11 citations
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December 2011 in “International journal of pharmaceutics” Ultrasound increases skin permeability but blocks hair follicles.
January 2026 in “ACS Applied Bio Materials” A new treatment using nanoliposomes can improve hair regrowth in androgenetic alopecia.
September 2025 in “Pharmaceutics” Quercetin nanocrystal gel shows promise for hair regrowth in androgenetic alopecia.
62 citations
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November 2016 in “Nanoscale” Medium to larger nanogels effectively deliver drugs through hair follicles when heated.
16 citations
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March 2008 in “International journal of pharmaceutics” Different factors like pH, gel type, and chemical enhancers affect how well hydrocortisone gets into hair follicles, and less hydrated skin doesn't work well with the test method.
Pseudofolliculitis causes painful bumps and dark spots from shaving, especially in people with curly hair, and can be treated by changing shaving habits and using specific topical treatments.
25 citations
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June 2015 in “Clinical, Cosmetic and Investigational Dermatology” Microneedling helps increase the absorption of a melanin product into hair follicles, which may improve laser hair removal effectiveness.
12 citations
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April 2020 in “Facial Plastic Surgery Clinics of North America” Follicular Unit Excision (FUE) is a popular, safe hair transplant method that avoids scars and has a quick recovery, but requires precise surgical skill.
19 citations
,
December 2013 in “European journal of pharmaceutics and biopharmaceutics” Encapsulated Garcinia mangostana extract in cream penetrates skin better than other forms.
55 citations
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January 2002 in “Journal of liposome research” New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.
12 citations
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July 2020 in “International Journal of Pharmaceutics” Iron oxide nanoparticles improve skin penetration and drug release for hair loss treatment.
9 citations
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July 2017 in “Journal of Drug Delivery Science and Technology” Scientists developed a new method to deliver alopecia treatment directly to hair follicles, which could be a promising treatment for hair loss and other hair diseases.
5 citations
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July 2019 in “Photodiagnosis and photodynamic therapy” Using tacalcitol ointment with photodynamic therapy may effectively treat follicular mucinosis with scalp hair loss.
4 citations
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June 2020 in “Journal of Cosmetic Dermatology” The edge out punch is a tool that lowers the chance of damaging hair follicles during hair transplant surgery.
The new microneedle system improves hair growth in alopecia treatment.
89 citations
,
November 2014 in “International Journal of Nanomedicine” Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.
32 citations
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March 2013 in “Journal of Pharmaceutical Sciences” Iontophoresis improves minoxidil delivery for alopecia treatment.
31 citations
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September 2014 in “Journal of Pharmaceutical Sciences” Using a special laser can improve how well hair loss treatments get into the skin and hair follicles.
15 citations
,
November 2020 in “Pharmaceutics” Tofacitinib nanoparticles can safely and effectively treat alopecia areata by targeting hair follicles.
11 citations
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May 2010 in “Journal of Medicinal Chemistry” A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
February 2024 in “Pharmaceutical research” Hair follicles affect how well small molecules can pass through the skin, and this varies depending on the molecule's features.
27 citations
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September 2018 in “Medicines” Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.
67 citations
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January 2012 in “Biological and Pharmaceutical Bulletin” Nanoparticles don't penetrate intact skin but can enter through pores or damaged skin.