8 citations
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October 2020 in “Pharmaceutics” Dutasteride-loaded nanoparticles coated with Lauric Acid-Chitosan show promise for treating hair loss due to their controlled release, low toxicity, and potential to stimulate hair growth.
522 citations
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January 2001 in “Cancer investigation” Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.
369 citations
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June 2013 in “Biochimie” Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.
277 citations
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July 2002 in “Molecular Endocrinology” Removing part of the vitamin D receptor stops vitamin D from working properly.
249 citations
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April 2002 in “The FASEB journal” Human skin can make serotonin and melatonin.
236 citations
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July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
152 citations
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April 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery” Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.
128 citations
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March 2016 in “Advanced Pharmaceutical Bulletin” Smaller nanoparticles penetrate skin better, especially through hair follicles.
113 citations
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November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
102 citations
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February 2008 in “The FASEB Journal” One minoxidil-sensitive potassium channel exists in human hair follicles.
99 citations
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December 2010 in “Journal of The European Academy of Dermatology and Venereology” The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.
92 citations
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September 2015 in “Journal of Lipid Research” Skin fat helps with body temperature control and has other active roles in health.
80 citations
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January 1995 in “The American Journal of Medicine” Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
77 citations
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March 2001 in “Clinics in Dermatology” Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
76 citations
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August 2018 in “International Journal of Cosmetic Science” Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
72 citations
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January 2001 in “Drugs” Minoxidil and finasteride treat hair loss; more research needed for other options.
65 citations
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October 2008 in “Journal of Neuroendocrinology”
62 citations
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October 2010 in “Journal of biomedical nanotechnology” Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
62 citations
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July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
58 citations
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March 2019 in “Experimental Dermatology” Exosomes from human skin cells can stimulate hair growth and could potentially be used for treating hair loss.
53 citations
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February 2020 in “Expert Opinion on Pharmacotherapy” Finasteride and minoxidil work best together for hair loss.
47 citations
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July 2014 in “European Journal of Pharmaceutics and Biopharmaceutics” Scientists created a gel with nanoparticles to deliver medicine to hair follicles effectively.
46 citations
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January 2020 in “Theranostics” Injecting a special gel with human protein particles can help hair grow.
46 citations
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September 2016 in “Clinical, Cosmetic and Investigational Dermatology” Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.
41 citations
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September 2014 in “Journal of Pharmacy and Pharmacology” Melatonin may help treat PCOS symptoms in rats.
39 citations
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August 2018 in “Scientific reports” Claudin-1 is important for the barrier function and growth of hair.
33 citations
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June 2007 in “International Journal of Pharmaceutics” The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.
29 citations
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February 2018 in “Genetics research international” Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.
27 citations
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September 2018 in “Skin appendage disorders” Hair transplantation may work for some types of scarring alopecia, but results vary and more research is needed.
25 citations
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July 2019 in “Experimental Dermatology” Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.