28 citations
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November 1987 in “Journal of the American Academy of Dermatology” The model successfully grew and differentiated hair follicle cells in the lab.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Apoptotic cells may trigger cell death in hair follicles during their regression cycle.
36 citations
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April 2016 in “Biochimie” A substance called epidermal growth factor helps increase the growth of important hair follicle cells by activating a specific cell communication route.
148 citations
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October 1997 in “Journal of Investigative Dermatology”
October 2023 in “Oncotarget” Apoptotic cells help cause hair follicle cell death during regression.
July 2025 in “Journal of Investigative Dermatology” Wnt and SHH pathways help form hair follicles by coordinating cell processes.
April 2017 in “Plastic and reconstructive surgery. Global open” Baby and adult skin cells are different, with baby cells having more active pathways that could help grow new hair follicles.
1010 citations
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August 2000 in “Cell” Hair follicle stem cells can form both hair follicles and skin.
34 citations
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August 1966 in “Experimental cell research” Keratin fibrils in hair form and stop growing at specific points in the follicle.
28 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Dermal papilla cells are crucial for hair growth and can induce new hair follicles.
August 2012 in “Nature Cell Biology” Hair grows when stem cell offspring in the follicle base proliferate, influenced by the dermal papilla.
2 citations
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June 2001 in “American Journal of Pathology” The document concludes that understanding how hair follicles naturally die and regenerate is important for insights into organ development and could impact health and disease treatment.
Fgf20 helps form hair follicle structures by stopping cell division and increasing cell movement.
11 citations
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May 1995 in “The journal of investigative dermatology/Journal of investigative dermatology” 854 citations
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February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
8 citations
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October 2024 in “Developmental Cell”
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Changing the structure of the hair follicle's environment can affect hair quality but doesn't stop hair growth.
2 citations
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January 2020 in “Methods in molecular biology” Scientists created early-stage hair follicles from human skin cells, which could help treat baldness and study hair growth.
August 2013 in “International Wound Journal” Non-hairy skin cells might be used to regenerate hair, helping with baldness and skin wounds.
December 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” New cells join the hair's dermal papilla during the growth phase, possibly affecting hair thickness.
26 citations
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January 2019 in “Experimental Dermatology” Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.
479 citations
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January 2005 in “BioEssays” Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
4 citations
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July 2022 in “Frontiers in Cell and Developmental Biology” The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.
16 citations
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November 2020 in “In Vitro Cellular & Developmental Biology - Animal” Microfollicles can effectively model human hair follicles for research and testing.
Injecting follicular cells into skin can lead to the formation of new hair follicles.
January 2003 in “Chinese Journal of Reparative and Reconstructive Surgery” Dermal papilla cells can help form hair follicles and produce hair.
87 citations
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February 2000 in “Journal of Investigative Dermatology” Stem cells in developing hair follicles move to specific areas as they mature.
142 citations
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June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Hair follicle stem cells can generate all hair cell types, skin, and sebaceous glands.
6 citations
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February 2012 in “American Journal of Animal and Veterinary Sciences” Growth factors are crucial for hair follicle growth and development.
35 citations
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July 2018 in “Cell Reports” The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.