December 2023 in “Frontiers in endocrinology” Excess androgens may cause PCOS, not just be a symptom.
October 2023 in “Benha Journal of Applied Sciences” Insulin resistance may contribute to hair loss in people with androgenic alopecia.
November 2020 in “Elsevier eBooks” Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
November 2019 in “Harper's Textbook of Pediatric Dermatology” The document is a detailed medical reference on skin and genetic disorders.
January 2017 in “International journal of clinical & experimental dermatology” Eating a balanced diet with vitamins, micronutrients, and antioxidants is important for hair health and can help with hair loss.
35 citations
,
May 1986 in “Clinics in endocrinology and metabolism” The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.
34 citations
,
September 2009 in “International Journal of Dermatology” Using anabolic-androgenic steroids can cause skin problems like acne and hair loss in athletes.
22 citations
,
November 2011 in “Journal of Analytical Toxicology” Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
January 2026 in “Food and Nutrition Sciences” USPlus PRO saw palmetto extract improves urinary symptoms and is safe for men.
June 2023 in “SPIRE - Sciences Po Institutional REpository” Extracellular vesicles and androgen receptors may help identify prostate cancer resistance and reduce SARS-CoV-2 infection.
February 2010 in “ePrints Soton (University of Southampton)” Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.
83 citations
,
April 1992 in “Clinical Endocrinology” Having enough iron improves the effectiveness of a specific hair loss treatment in women.
27 citations
,
January 2002 in “Exogenous Dermatology” Chronic exposure to sunlight may worsen male pattern baldness and protecting the scalp from the sun could slow it down.
378 citations
,
November 2011 in “Human reproduction update” Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.
9 citations
,
January 1997 in “Gynecological Endocrinology” The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
1 citations
,
April 2006 in “Seminars in Reproductive Medicine” Androgen therapy might help some women with low libido, but it has risks and should be used carefully.
December 2015 in “University of Birmingham Institutional Research Archive (University of Birmingham)” AKR1C3 could be a treatment target for metabolic issues in PCOS.
157 citations
,
April 1994 in “Clinical endocrinology” Androgens can cause hair growth in some areas and hair loss on the scalp.
135 citations
,
March 1984 in “Fertility and sterility” Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.
105 citations
,
January 2009 in “Medicine” Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.
93 citations
,
February 2009 in “Annals of the New York Academy of Sciences” 5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.
92 citations
,
January 1998 in “Dermatology” Ketoconazole shampoo improves hair growth and reduces oil similarly to minoxidil in male pattern hair loss.
63 citations
,
March 2011 in “Clinical Endocrinology” Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.
48 citations
,
February 2014 in “Fertility and Sterility” Women with PCOS often have hair loss, which is linked to acne or excess body hair but not to worse hormone or metabolic issues.
47 citations
,
December 2019 in “Biomaterials” Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
37 citations
,
June 2011 in “Journal of Cellular Biochemistry” Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
31 citations
,
November 2014 in “Journal of Endocrinological Investigation” Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.
29 citations
,
July 2013 in “The Journal of Sexual Medicine” Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.
26 citations
,
November 1993 in “Progress in Neuro-psychopharmacology & Biological Psychiatry” Treatment during development affects hormone balance and sexual behavior in male rats.
25 citations
,
August 2006 in “Human Reproduction” Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.