92 citations
,
January 1999 in “Physics in Medicine and Biology” Skin can be cooled quickly and safely during laser treatments to protect it without affecting deeper layers.
December 2025 in “Journal of Pharma Insights and Research.” Injectable cryogels can deliver drugs and aid tissue repair with minimal surgery.
7 citations
,
December 2015 in “Journal of thermal biology” Scalp cooling devices need to be powerful enough to overcome heat loss and reach the right temperature to prevent hair loss from chemotherapy.
14 citations
,
January 2014 in “Anais Brasileiros de Dermatologia” Low BMI and cold exposure increase the risk of chilblains.
48 citations
,
October 2011 in “Sports Medicine” Ice-skating athletes often have skin problems due to cold, infections, and inflammation, needing careful treatment and prevention.
21 citations
,
September 2016 in “Breast” Cooler scalp temperatures during chemotherapy may prevent hair loss.
July 2021 in “MVP journal of medical science” Liquid Nitrogen Cryotherapy effectively treats unresponsive Alopecia Areata with minimal side effects.
3 citations
,
May 2019 in “Medical Hypotheses” A new hair transplant method suggests freezing and storing dense hairs for future use to address severe hair loss.
31 citations
,
September 1999 in “Dermatologic Surgery” Cooling hair micrografts during transplantation does not improve their survival or growth.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Hair follicles can be kept in RNAlater® at cool or room temperature for a week without harming RNA quality.
June 2019 in “Problems of Cryobiology and Cryomedicine” 11 citations
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October 2020 in “PLoS ONE” Cooling can protect hair follicles from chemotherapy damage by reducing drug uptake.
The treatment showed promising results in improving advanced-stage hair loss.
13 citations
,
January 2020 in “Annals of Oncology” Cryotherapy and compression therapy might help prevent chemotherapy nerve damage, but more research is needed.
4 citations
,
July 2025 in “Frontiers in Pharmacology” Cooling with antioxidants helps protect hair during chemotherapy.
March 2025 in “International Journal of Trichology” Storing hair follicles in 10% DMEM at 37°C improves hair transplant success.
3 citations
,
May 2011 in “Medical Hypotheses” Transnasal cooling could reveal new insights into various physiological conditions and may be a natural way to transfer heat from the brain.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Freezing gamma-irradiated amniotic fluid may help hair growth and speed up the growth phase.
15 citations
,
October 2006 in “Journal of the American Academy of Dermatology” Liquid nitrogen spray caused a temporary, harmless swelling under the skin in an elderly woman.
Human hair keratins can be turned into useful 3D biomedical scaffolds through a freeze-thaw process.
16 citations
,
June 2019 in “Industrial Biotechnology” Freezing brown seaweed right after harvesting and using microwave-assisted extraction with 75% 1,3-propanediol as a solvent is the best way to get polyphenols for cosmetics.
15 citations
,
January 2003 in “Lasers in Surgery and Medicine” Cold air and a chilled sapphire window both protect the skin during laser treatments, and work better with water or gel, especially for darker skin.
29 citations
,
September 2020 in “International Journal of Molecular Sciences” The document concludes that freeze-dried platelet-rich plasma shows promise for medical use but requires standardization and further research.
March 2025 in “Tissue and Cell” Frozen-thawed fibroblast sheets enhance wound healing and hair growth in mice.
8 citations
,
November 2019 in “Journal of Natural Fibers” Adding human hair to clayey soil makes it stronger, even after freeze-thaw cycles, and is eco-friendly and cheap.
7 citations
,
September 2024 in “Scientific Reports” Sebum samples remain stable under various storage conditions, making them suitable for remote and at-home testing.
1 citations
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August 2024 in “Journal of Dermatological Science” Cold shock therapy may help hair grow by increasing certain proteins.
2 citations
,
March 2024 in “Supportive Care in Cancer” Penguin Cold Caps help most patients keep at least half their hair during chemotherapy.
January 2021 in “Mastology” Scalp cooling therapy helped over 80% of women keep at least half their hair during chemotherapy.
4 citations
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March 2024 in “Journal of the American Academy of Dermatology” Scalp cooling therapy is costly and often not covered by insurance, limiting access for low-income patients.