19 citations
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January 2015 in “Scientific Reports” GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.
5 citations
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November 2011 in “Journal of Cutaneous Medicine and Surgery” Hairless dogs can be used to study human hypertrophic scars.
46 citations
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September 2013 in “PLOS ONE” Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.
46 citations
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December 2001 in “Journal of Endocrinology/Journal of endocrinology” FLRG and follistatin have different roles in wound healing.
Stem cell therapy shows promise for better burn healing but needs more research and standardization.
105 citations
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December 2017 in “Journal of Biological Engineering” Artificial skin grafts face immune rejection, but stem cells may improve future designs.
June 2019 in “PRISM (University of Calgary)” DPCs and new biomaterials can greatly improve skin healing.
November 2024 in “Burns & Trauma” Skin organoids help improve wound healing and tissue repair.
January 2022 in “Pastic and aesthetic research” PRP helps skin regeneration but needs standardized testing for consistent results.
1 citations
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July 2025 in “Journal of Investigative Dermatology” Increasing m6A levels can improve skin cell growth and wound healing.
56 citations
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March 2016 in “International Wound Journal” Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.
359 citations
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January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
52 citations
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February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
328 citations
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November 2020 in “Nature Materials” Hydrogel scaffolds can help wounds heal better and grow hair.
159 citations
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January 2006 in “BMC Cell Biology” Wnt signaling can improve skin healing by promoting epithelial growth.
44 citations
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October 2019 in “International Journal of Molecular Sciences” Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.
14 citations
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January 2025 in “Biomaterials Research” Bioactive glasses help heal skin wounds by promoting tissue repair and preventing infections.
7 citations
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June 2022 in “Frontiers in Medicine” ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.
4 citations
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December 2023 in “Advanced science” New injectable hydrogels with gelatin, metal, and tea polyphenols help heal diabetic wounds faster by controlling infection, improving blood vessel growth, and managing oxidative stress.
3 citations
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March 2023 in “Life” Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.
2 citations
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April 2023 in “Stem Cell Research & Therapy” Tiny fat-derived particles can help repair soft tissues by changing immune cell types.
January 2025 in “PLoS ONE” Aligned membranes improve wound healing by reducing scars and promoting skin regeneration.
7 citations
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November 2020 in “Experimental Dermatology” Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
28 citations
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April 2024 in “Immunity” CD80 on skin stem cells helps expand Treg cells to aid wound healing.
35 citations
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September 2009 in “Development” Necl2 affects skin cell behavior and slows wound healing.
M-CSF-stimulated myeloid cells can turn into skin cells and help heal wounds and regrow hair.
25 citations
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April 2021 in “The EMBO Journal” Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
February 2026 in “PubMed” Porcine-derived placental powder may improve wound healing by reducing inflammation and enhancing tissue repair.
238 citations
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March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
14 citations
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January 2019 in “Advances in experimental medicine and biology” Skin stem cells are promising for healing wounds and skin regeneration due to their accessibility and regenerative abilities.