research Anabolic-androgenic steroids and cardiovascular risk
Using steroids can increase the risk of heart problems.
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research Omega 3 fatty acid-enriched nanoemulsion of thiocolchicoside for transdermal delivery: formulation, characterization and absorption studies
The new formulation improved the skin absorption of the drug Thiocolchicoside.
research Gilles de la Tourette syndrome – A treatable condition?
Gilles de la Tourette syndrome is treatable, with behavioral therapy as a recommended first option and other treatments available for more severe cases.
research Applications of Nanostructured Lipid Carriers: Recent Advancements and Patent Review
Nanostructured lipid carriers are promising for improving drug delivery in medicine and food.
research The role of dermocosmetics in the management of cancer-related skin toxicities: international expert consensus
Dermocosmetics help manage skin issues in cancer patients, improving outcomes and reducing treatment interruptions.
research Molecular basis of androgen action on human sexual desire
Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.
research Update on psychodermatological disorders
Treating both the mind and skin together, especially by managing stress, can greatly improve outcomes for skin disorders linked to psychological issues.
research Beneficial effects of zinc on reducing severity of depression
Zinc helps reduce the severity of depression.
research Farmácia Serpa Pinto, Porto e Serviços Farmacêuticos do Instituto Português Oncologia do Porto Francisco Gentil, EPE, Porto
Dutasteride is more effective than finasteride for hair growth, and pregabalin effectively treats neuropathic pain.
research Study of association between valproic acid levels, biotinidase activity and hair loss in Indian population: A cross-sectional comparative study
Valproic acid treatment may cause hair loss due to reduced biotinidase activity.
research Endogenous neurosteroids modulate epileptogenesis in a model of temporal lobe epilepsy
Neurosteroids may help prevent seizures in epilepsy.
research Case report: a study of the clinical characteristics and genetic variants of post-finasteride syndrome patients
Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.
research Formulation and Evaluation of Valproic Acid Microemulsions for Enhanced Transfollicular Delivery in Guinea Pig Skin
Valproic acid microemulsions improve skin delivery compared to regular solutions.
research Dermatologic adverse events associated with afatinib: an oral ErbB family blocker
Afatinib often causes skin problems that need proactive management.
research A Mouse Kindling Model of Perimenstrual Catamenial Epilepsy
Neurosteroids help reduce seizures, but their withdrawal increases seizure activity.
research The connection of 5-alpha reductase inhibitors to the development of depression
5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.
research Depression risk of 5-alpha reductase inhibitors: impact of active-comparator versus non-drug user control groups on risk measurement
5-alpha reductase inhibitors slightly increase depression risk, but the risk varies based on the control group used.
research Retrospective Assessment of Changes in Perceived Health Status during Continuous Use of a Dietary Supplement
Most people using the supplement Renew saw health improvements, especially in sleep and energy, faster than with regular vitamins.
research Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats
Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.
research Novel modulatory effects of neurosteroids and benzodiazepines on excitatory and inhibitory neurons excitability: a multi-electrode array recording study
Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.
research Activation of extrasynaptic δ-GABAA receptors globally or within the posterior-VTA has estrous-dependent effects on consumption of alcohol and estrous-independent effects on locomotion
δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.
research An overview on 5α-reductase inhibitors
5α-reductase inhibitors, like Finasteride and Dutasteride, help manage benign prostatic hyperplasia.
research Involvement of neurosteroids in the anxiolytic-like effects of AC-5216 in mice
AC-5216 reduces anxiety in mice through neurosteroids affecting GABAA receptors.
research Advancements and challenges in stem cell transplantation for regenerative medicine
Stem cell transplantation shows promise for treating diseases but faces challenges like safety, ethics, and cost.
research Lack of evidence of a role for the neurosteroid allopregnanolone in ethanol-induced reward and c-fos expression in DBA/2 mice
Allopregnanolone likely doesn't influence ethanol's rewarding effects in these mice.
research Hepatocyte growth factor-modified hair follicle stem cells ameliorate cerebral ischemia/reperfusion injury in rats
HGF-modified hair follicle stem cells help brain recovery after injury in rats.
research Docking and Molecular Dynamics Identify Leads against 5 Alpha Reductase 2 for Benign Prostate Hyperplasia Treatment
New compounds show promise for treating benign prostate hyperplasia with fewer side effects.
research Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells
Allopregnanolone changes gene expression in glioblastoma cells.
research Mitochondrial dysfunction in an animal model of diabetic neuropathy is associated with a reduction of neurosteroid synthesis.
Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.
research Fermented Yeast Complex Extract Promotes Hair Regrowth by Decreasing Oxidative Stress
Fermented Yeast Complex Extract helps regrow hair by reducing oxidative stress and inflammation.