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GlossaryGel Electrophoresis

Gel electrophoresis is a laboratory technique used to separate DNA, RNA, or proteins based on their size and charge. In the context of hair loss research, it is relevant for analyzing genetic markers associated with hair loss conditions, as well as for studying the expression of specific proteins involved in hair follicle biology. Key distinguishing characteristics include the use of a gel matrix, typically agarose or polyacrylamide, which allows for the migration of molecules when an electric current is applied, enabling researchers to visualize and compare genetic or protein samples.

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Electrophoretic Variability in Human Head Hair: Polyacrylamide Gel Electrophoresis of Hair Proteins in the Presence of Sodium Dodecyl Sulfate and Urea

research Electrophoretic variability in human head hair: Polyacrylamide gel electrophoresis of hair proteins in the presence of sodium dodecyl sulfate and urea

15 citations , January 1987 in “Electrophoresis”

Human head hair proteins can be typed into eight distinct patterns, useful for genetic and forensic investigations.

Electrophoretic Variability in Human Hair: Comparative Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis of Body and Head Hair Proteins

research Electrophoretic variability in human hair: Comparative sodium dodecyl sulfate‐polyacrylamide gel electrophoresis of body and head hair proteins

11 citations , January 1987 in “Electrophoresis”

Keratin proteins are consistent across different hair types from the same person.

research Development of high-performance two-dimensional gel electrophoresis for human hair shaft proteome

13 citations , March 2019 in “PLoS ONE”

A new method improves protein analysis in hair, aiding health and disease research.

research Analysis of the abnormal human hair keratins by two-dimensional polyacrylamide gel electrophoresis

March 1990 in “Journal of Dermatological Science”

research [Analysis of normal human hair keratins by two-dimensional polyacrylamide gel electrophoresis].

May 1988 in “PubMed”

research A genetic electrophoretic variant of high-sulfur hair proteins for forensic hair comparisons. II. Practical application of electrophoretic analysis of hair protein to forensic hair comparisons.

1 citations , February 1989 in “PubMed”

Electrophoresis can effectively analyze hair proteins for forensic use, even after cosmetic treatments and up to 2 years of weathering.

research Solid basal cell epithelioma (BCE) possibly originates from the outer root sheath of the hair follicle.

61 citations , August 1993 in “PubMed”

Basal cell epithelioma likely starts from the hair follicle's outer root sheath.

research Hair Keratins and Hair Follicle–Specific Epithelial Keratins

31 citations , January 2004 in “Methods in cell biology”

Hair and follicle keratins differ in structure and expression, especially in cysteine content.

research Potential use of human hair shaft keratin peptide signatures to distinguish gender and ethnicity

22 citations , January 2020 in “PeerJ”

Keratin peptides in hair might help identify gender and ethnicity.

research Extraction of keratin particles as intact protein sequences from chicken feathers and their characterization

January 2026 in “Biomaterials and Biosystems”

Keratin from chicken feathers can be safely used on damaged skin.

research Extraction of keratin particles as intact protein sequences from chicken feathers and their characterization

January 2026 in “Digitalen Hochschulbibliothek Sachsen-Anhalt (Universitäts- und Landesbibliothek Sachsen-Anhalt)”

Keratin from chicken feathers can be safely used for skin benefits.

research Peer Review #2 of "Potential use of human hair shaft keratin peptide signatures to distinguish gender and ethnicity (v0.1)"

January 2020

Keratin peptide signatures in hair may help identify gender and ethnicity.

research Peer Review #1 of "Potential use of human hair shaft keratin peptide signatures to distinguish gender and ethnicity (v0.2)"

January 2020

Keratin peptide signatures in hair may help identify gender and ethnicity.

research Peer Review #1 of "Potential use of human hair shaft keratin peptide signatures to distinguish gender and ethnicity (v0.1)"

January 2020

Keratin peptides in hair may help identify gender and ethnicity, but more research is needed.

research Enzyme Typing of Human Hair Roots

27 citations , April 1978 in “Journal of Forensic Sciences”

Enzyme typing can reliably characterize human hair.

research Characterization of the cysteine-rich calcium-binding S100A3 protein from human hair cuticles

17 citations , December 2002 in “Biochemical and biophysical research communications”

Scientists found out how a specific protein in human hair cuticles behaves and is structured.

research Polymorphic Enzyme Systems in Human Hair Sheath Cells

11 citations , April 1982 in “Journal of the Forensic Science Society”

Enzyme presence in hair sheath cells decreases over time, affecting forensic analysis.

Proteomic Analysis Identifies Differentially Expressed Proteins Participating in Forming Type III Brush Hair in Yangtze River Delta White Goat

research Proteomic analysis identifies differentially expressed proteins participating in forming Type III brush hair in Yangtze River Delta white goat

8 citations , January 2015 in “Genetics and molecular research”

Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.

Proteomic Tools for the Investigation of Human Hair Structural Proteins and Evidence of Weakness Sites on Hair Keratin Coil Segments

research Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments

38 citations , October 2011 in “Analytical biochemistry”

Hair proteins have weak spots in their α-helical segments.

In Vitro Assembly Properties of Human Type I and II Hair Keratins

research <i>In vitro</i> Assembly Properties of Human Type I and II Hair Keratins

12 citations , January 2014 in “Cell structure and function”

Different combinations of human hair keratins affect how hair fibers form.

research Biochemical examination of fetal skin biopsy specimens obtained by fetoscopy: Use of the method for analysis of keratins and filaggrin

7 citations , January 1986 in “Prenatal Diagnosis”

Fetal skin biopsy can help diagnose protein-related disorders before birth.

research Proliferating trichilemmal cyst with histological malignant transformation: Identification of hair sheath keratins in the tumor.

3 citations , January 1989 in “The Nishinihon Journal of Dermatology”

A hair cyst can become cancerous, showing specific keratins from the hair sheath.

research The microfibrillar proteins of human hair: Separation by high-performance liquid chromatography and isolation of some proteins enriched in glycine and tyrosine

2 citations , August 1987 in “Analytical Biochemistry”

A new method isolated previously undetected hair proteins rich in glycine and tyrosine.

research [The complex detection of AB(O)-system antigens and of keratin polymorphism in the forensic medical study of hair].

June 1997 in “PubMed”

A 5 cm hair sample can reveal blood type and keratin type for forensic use.

research Transfollicular enhancement of gel containing cationic niosomes loaded with unsaturated fatty acids in rice (Oryza sativa) bran semi-purified fraction

21 citations , April 2012 in “European Journal of Pharmaceutics and Biopharmaceutics”

The gel with special fat-loaded particles from rice bran could be an effective skin treatment for hair loss.

In Vitro–In Vivo Assessments of Apocynin-Hybrid Nanoparticle-Based Gel as an Effective Nanophytomedicine for Treatment of Rheumatoid Arthritis

research In vitro–in vivo assessments of apocynin-hybrid nanoparticle-based gel as an effective nanophytomedicine for treatment of rheumatoid arthritis

11 citations , June 2023 in “Drug Delivery and Translational Research”

The gel with apocynin-loaded nanoparticles shows promise for treating rheumatoid arthritis.

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Related Terms

Research

research Electrophoretic variability in human head hair: Polyacrylamide gel electrophoresis of hair proteins in the presence of sodium dodecyl sulfate and urea

research Electrophoretic variability in human hair: Comparative sodium dodecyl sulfate‐polyacrylamide gel electrophoresis of body and head hair proteins

research Development of high-performance two-dimensional gel electrophoresis for human hair shaft proteome

research Analysis of the abnormal human hair keratins by two-dimensional polyacrylamide gel electrophoresis

research [Analysis of normal human hair keratins by two-dimensional polyacrylamide gel electrophoresis].

research A genetic electrophoretic variant of high-sulfur hair proteins for forensic hair comparisons. II. Practical application of electrophoretic analysis of hair protein to forensic hair comparisons.

research Solid basal cell epithelioma (BCE) possibly originates from the outer root sheath of the hair follicle.

research Hair Keratins and Hair Follicle–Specific Epithelial Keratins

research Potential use of human hair shaft keratin peptide signatures to distinguish gender and ethnicity

research Extraction of keratin particles as intact protein sequences from chicken feathers and their characterization

research Extraction of keratin particles as intact protein sequences from chicken feathers and their characterization

research Peer Review #2 of "Potential use of human hair shaft keratin peptide signatures to distinguish gender and ethnicity (v0.1)"

research Peer Review #1 of "Potential use of human hair shaft keratin peptide signatures to distinguish gender and ethnicity (v0.2)"

research Peer Review #1 of "Potential use of human hair shaft keratin peptide signatures to distinguish gender and ethnicity (v0.1)"

research Enzyme Typing of Human Hair Roots

research Characterization of the cysteine-rich calcium-binding S100A3 protein from human hair cuticles

research Polymorphic Enzyme Systems in Human Hair Sheath Cells

research Proteomic analysis identifies differentially expressed proteins participating in forming Type III brush hair in Yangtze River Delta white goat

research Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments

research <i>In vitro</i> Assembly Properties of Human Type I and II Hair Keratins

research Biochemical examination of fetal skin biopsy specimens obtained by fetoscopy: Use of the method for analysis of keratins and filaggrin

research Proliferating trichilemmal cyst with histological malignant transformation: Identification of hair sheath keratins in the tumor.

research The microfibrillar proteins of human hair: Separation by high-performance liquid chromatography and isolation of some proteins enriched in glycine and tyrosine

research [The complex detection of AB(O)-system antigens and of keratin polymorphism in the forensic medical study of hair].

research Electrophoretic variation of hair proteins.

research The up‐regulation of 14‐3‐3 proteins in Smad4 deficient epidermis and hair follicles at catagen

research Locations of synthesis of hair structural proteins in human anagen follicles

research Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding?

research Transfollicular enhancement of gel containing cationic niosomes loaded with unsaturated fatty acids in rice (Oryza sativa) bran semi-purified fraction

research In vitro–in vivo assessments of apocynin-hybrid nanoparticle-based gel as an effective nanophytomedicine for treatment of rheumatoid arthritis