January 2026 in “Diagnostics” This study compared the diagnostic accuracy of four publicly available large language models (LLMs) with that of 15 dermatologists, including residents, board-certified dermatologists, and trichology experts, in interpreting trichoscopic images. The dermatologists achieved a diagnostic accuracy of 58.1% for a single suspected diagnosis and 68.3% when including differential diagnoses, with experts outperforming others. In contrast, the LLMs had a significantly lower accuracy of 18.2% for a single diagnosis and 44.4% for including differential diagnoses, with Gemini 2.5 Flash performing best among the models. The agreement between AI models and dermatologists was slight to fair, indicating that LLMs currently underperform compared to human experts in trichology. The study concludes that LLMs need further development and specialized training to be reliable in assisting with trichological diagnoses.
October 2025 in “Dermatology Practical & Conceptual” ChatGPT 4.0 and Gemini 1.5 Flash are effective for educating patients about androgenetic alopecia, while Deepseek R1 is less reliable.
8 citations
,
June 1995 in “Helvetica Chimica Acta” Compound 15a was effective in inhibiting 5α-reductase.
5 citations
,
November 2015 in “Journal of Enzyme Inhibition and Medicinal Chemistry” Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
November 2025 in “Discover Pharmaceutical Sciences” The essential oils nanoemulsion promotes hair growth better than 2% minoxidil in mice.
8 citations
,
November 2019 in “Journal of Natural Fibers” Adding human hair to clayey soil makes it stronger, even after freeze-thaw cycles, and is eco-friendly and cheap.
10 citations
,
May 2016 in “Polymer” New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.
23 citations
,
January 2001 in “Chemical & Pharmaceutical Bulletin” New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
70 citations
,
February 2019 in “The journal of immunology/The Journal of immunology” Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.
3 citations
,
January 2003 in “Synthetic Communications” Scientists made two new chemicals that might help treat diseases caused by male hormones.
23 citations
,
January 2018 in “Elsevier eBooks” Nanoemulsions improve stability and delivery of active ingredients in cosmetics for skin and hair care.
50 citations
,
April 2010 in “Biology direct” Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
8 citations
,
October 2022 in “International Journal of Molecular Sciences” The hydrogels improved healing in deep second-degree burns.
September 2023 in “Pharmaceuticals” Tiny particles improved delivery of hair loss treatments to hair follicles, with lipid-based particles performing best.
1 citations
,
September 2025 in “PLOS Digital Health” Large language models often give biased or inaccurate medical responses, especially for LGBTQIA+ prompts.
51 citations
,
September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
7 citations
,
May 2016 in “European Polymer Journal” The new nanocarriers improve how well water-insoluble drugs dissolve and allow for controlled drug release.
207 citations
,
January 2011 in “Dermatologic Therapy” Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.
February 2010 in “ePrints Soton (University of Southampton)” Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.
124 citations
,
June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
19 citations
,
August 2014 in “Journal of Ethnopharmacology” The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
76 citations
,
February 2015 in “Industrial Crops and Products” Researchers found over 40 compounds in Bituminaria bituminosa, including many flavonoids and some with potential for medical and hair care uses.
3D culture better preserves sweat gland cell identity than 2D culture.
December 2023 in “Pharmaceutics” The new adhesive nanoparticles are effective for delivering Minoxidil to the scalp without skin irritation.
April 2026 in “Diagnostics” Skin changes in obesity can indicate metabolic issues but aren't reliable for assessing risk or monitoring treatment.
11 citations
,
March 2023 in “Stem Cell Research & Therapy” Epidermal stem cells improve skin graft survival by promoting early blood vessel formation.
13 citations
,
July 2020 in “Stem Cell Research & Therapy” Young donor, early passage stem cells have the highest stemness.
25 citations
,
June 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” VDR regulation varies by tissue and is crucial for its biological functions.
1 citations
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January 2023 in “Chemical Engineering Journal” May 2026 in “Cell Reports Medicine” FR-1 reduces skin scarring and promotes healing without harmful effects.