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Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Gender-affirming hormone therapy improves mental health and gender incongruence but requires careful management of cardiovascular and cancer risks.

Gender affirming hormone therapy improves outcomes in gender affirmation surgery.

Gender-affirming hormone therapy in South Korea aligns with international guidelines and has specific side effects.

Gender-affirming hormone therapy and surgery affect gut bacteria differently.

Gender-affirming hormone therapy affects metabolism differently based on treatment type.

Feminizing hormone therapy increases kidney filtration rate.

Topical minoxidil helps transgender individuals assigned female at birth grow more facial hair.

Future hormone therapy trials should match the diverse needs and priorities of the gender-diverse community.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Gender-affirming hormone therapy changes hair growth in transgender people, with feminizing therapy reducing hair and masculinizing therapy increasing it, but sometimes additional treatment is needed.

Most transgender patients getting laser hair removal before gender-affirming surgery are already on hormone therapy, which might affect the hair removal process.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Testosterone treatment may affect heart response to stress in transgender men.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

Testosterone treatment may change estrogen receptor methylation in AFAB individuals.

Psoriasis rates in transgender people are similar to the general population, but hormone therapy might affect it.

The document concludes that respectful, gender-affirming healthcare improves mental health and encourages continued medical care for transgender and non-binary individuals.

Hormone therapy greatly improves the quality of life for adults seeking gender reaffirmation, but more research is needed in India.

The document advises health care providers on how to support transgender and gender-diverse youth with appropriate care and referrals.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Transmasculine individuals on testosterone therapy need tailored contraception and fertility advice due to unique risks and benefits of each contraceptive method.

Transgender and nonbinary individuals experience hair loss, with transmen on testosterone seeing more severe hair loss, while feminizing hormones may stabilize hair loss in transwomen.

The statement offers guidance for hormone therapy and surgery to help gender-incongruent adults affirm a male identity.

Athletic trainers should understand and support the medical needs of transgender and gender-diverse patients.

Transgender and gender-diverse teens need specialized skin and mental health care.

Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.

Transgender patients on masculinizing hormones have higher hair loss rates than cisgender women.

Care for gender-dysphoric Veterans can be improved with a consistent, team-based approach.